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- W3023357312 abstract "Allorecognition, the capacity to discriminate self from conspecific non-self, is a ubiquitous organismal feature typically governed by genes evolving under balancing selection. Here, we show that in the fungus Podospora anserina, allorecognition loci controlling vegetative incompatibility (het genes), define two reproductively isolated groups through pleiotropic effects on sexual compatibility. These two groups emerge from the antagonistic interactions of the unlinked loci het-r (encoding a NOD-like receptor) and het-v (encoding a methyltransferase and an MLKL/HeLo domain protein). Using a combination of genetic and ecological data, supported by simulations, we provide a concrete and molecularly defined example whereby the origin and coexistence of reproductively isolated groups in sympatry is driven by pleiotropic genes under balancing selection." @default.
- W3023357312 created "2020-05-13" @default.
- W3023357312 creator A5008616285 @default.
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- W3023357312 creator A5089998159 @default.
- W3023357312 date "2022-05-12" @default.
- W3023357312 modified "2023-10-01" @default.
- W3023357312 title "Allorecognition genes drive reproductive isolation in Podospora anserina" @default.
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