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- W3023395710 abstract "Publisher SummaryThis chapter explains about phytoestrogens. Phytoestrogens are non-steroidal, natural plant compounds that are structurally or functionally similar to mammalian estrogens, particularly 17β-estradiol. Typically, phytoestrogens or their active metabolites exert their estrogenic effect on the central nervous system and on the reproductive system of males and females, inducing estrus and stimulating growth of the genital tract and mammary glands in females; in fact, at many levels from the hypothalamic–pituitary level to local levels of the ovary and uterus, and testis and prostate gland through numerous mechanisms. Effects of phytoestrogens may vary with the individual phytoestrogen, species exposed, sex, the route, and dose and duration of exposure, particularly the timing during reproductive development and cycling. Phytoestrogens are excreted in milk, with animal diet playing a major role in detectable concentrations. A major focus of concern is phytoestrogen exposure of infants consuming soy-based formulas for months and its potential health effects. The effects of pre- and neonatal exposure to phytoestrogens on development in laboratory animals have been studied, with variable effects observed. The impact of phytoestrogens on human development is not clear. The focus of phytoestrogens is on both beneficial and adverse effects. Regarding the adverse impact of phytoestrogens on livestock fertility, the current recommendation is either to delete or dilute the estrogenic component of the diet. Because of the variability in multiple parameters of exposure of numerous phytoestrogens to experimental animals and humans, there are not adequate data to determine the developmental and reproductive toxicity of soy infant formula in humans." @default.
- W3023395710 created "2020-05-13" @default.
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- W3023395710 date "2011-01-01" @default.
- W3023395710 modified "2023-10-06" @default.
- W3023395710 title "Phytoestrogens" @default.
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- W3023395710 doi "https://doi.org/10.1016/b978-0-12-382032-7.10052-9" @default.
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