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- W3023414271 abstract "In a prospective controlled study mean systolic blood pressure had risen by 102 mmHg and mean diastolic pressure by 6·0 mmHg after 2 yr in 186 women taking oestrogen-progestogen oral contraceptives. After 5 yr, 15 of these women showed mean increases of 12·3 mmHg systolic and 8·8 mmHg diastolic. The greatest rise in systolic pressure was 41 mmHg and the highest systolic level reached was 168 mmHg. In two cases diastolic pressure increased by 34 and 24 mmHg to 94 and 98 mmHg respectively. In a second study no significant correlation was found between blood pressure and concurrent plasma concentrations of renin, renin-substrate, angiotensin II, aldosterone, cortisol or DOC in women taking oestrogen-progestogen steroid contraceptives. Total exchangeable sodium and potassium were not affected by oral contraceptive administration and there was no correlation between total exchangeable sodium and blood pressure." @default.
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- W3023414271 date "1976-01-01" @default.
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- W3023414271 title "CONTRACEPTIVE STEROIDS AND HYPERTENSION" @default.
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- W3023414271 doi "https://doi.org/10.1016/b978-0-08-019682-4.50133-5" @default.
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