FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3023496166> ?p ?o ?g. }

• W3023496166 endingPage "103891" @default.
• W3023496166 startingPage "103891" @default.
• W3023496166 abstract "In this research, curcumin (CUR) conjugated albumin based nanoparticles (BSA-CUR) were designed for improvement and evaluation radioprotective effect of CUR. In this way, we have prepared BSA-CUR by covalently binding the CUR with BSA. Next, this synthesized prodrug was evaluated for physical and chemical properties by Fourier-transform infrared (FTIR), Dynamic light scattering (DLS), Transmission electron microscopy (TEM), Ultraviolet–visible (UV/Vis), and Differential scanning calorimetry (DSC) analysis. Furthermore, the chemical stability of designed prodrug was appraised. The result shows that the size of nanoparticles is 174.4 nm with a polydispersity index (PdI) of 0.191. The nanoparticles have a high loading capacity and show sustained release behavior. Loading of CUR to BSA not only could increase the chemical stability of CUR, but also could improve radioprotection efficacy of it's against X-Ray irradiation. The HHF-2 cells show 107% viability in the presence of BSA-CUR at a concentration of 50 µg/mL, whereas non-treated cells show 46% viability, under X-Ray irradiation. Also in vivo study results show that, four out of five mice have died when the mice irradiated by X-Ray and no received any treatment. Although, for a group that treated with BSA-CUR and also irradiated by X-Ray, median survival and survival rate was higher than CUR treated and control mice, and only two out of five mice have died. The result of this study proved that BSA-CUR can be used as a proficient vehicle for improving the potential radioprotective effect of CUR." @default.
• W3023496166 created "2020-05-13" @default.
• W3023496166 creator A5005756615 @default.
• W3023496166 creator A5007053229 @default.
• W3023496166 creator A5030352385 @default.
• W3023496166 creator A5053495030 @default.
• W3023496166 creator A5057296536 @default.
• W3023496166 date "2020-07-01" @default.
• W3023496166 modified "2023-10-18" @default.
• W3023496166 title "Evaluation radioprotective effect of curcumin conjugated albumin nanoparticles" @default.
• W3023496166 cites W152873362 @default.
• W3023496166 cites W1971659905 @default.
• W3023496166 cites W1972125312 @default.
• W3023496166 cites W1975770667 @default.
• W3023496166 cites W1977920395 @default.
• W3023496166 cites W1987712541 @default.
• W3023496166 cites W1989133022 @default.
• W3023496166 cites W2024960745 @default.
• W3023496166 cites W2056023634 @default.
• W3023496166 cites W2056473947 @default.
• W3023496166 cites W2088946504 @default.
• W3023496166 cites W2104738536 @default.
• W3023496166 cites W2141909493 @default.
• W3023496166 cites W2170330790 @default.
• W3023496166 cites W2250673102 @default.
• W3023496166 cites W2306347491 @default.
• W3023496166 cites W2414781026 @default.
• W3023496166 cites W2473551710 @default.
• W3023496166 cites W2500007776 @default.
• W3023496166 cites W2579946261 @default.
• W3023496166 cites W2596775702 @default.
• W3023496166 cites W2604355116 @default.
• W3023496166 cites W2765634223 @default.
• W3023496166 cites W2770794472 @default.
• W3023496166 cites W2788428691 @default.
• W3023496166 cites W2789482518 @default.
• W3023496166 cites W2794580492 @default.
• W3023496166 cites W2884522637 @default.
• W3023496166 cites W2890815774 @default.
• W3023496166 cites W2909418106 @default.
• W3023496166 cites W2911913967 @default.
• W3023496166 cites W2922408224 @default.
• W3023496166 cites W2950964394 @default.
• W3023496166 cites W2965909654 @default.
• W3023496166 cites W3003210281 @default.
• W3023496166 cites W3012791995 @default.
• W3023496166 doi "https://doi.org/10.1016/j.bioorg.2020.103891" @default.
• W3023496166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32422388" @default.
• W3023496166 hasPublicationYear "2020" @default.
• W3023496166 type Work @default.
• W3023496166 sameAs 3023496166 @default.
• W3023496166 citedByCount "23" @default.
• W3023496166 countsByYear W30234961662021 @default.
• W3023496166 countsByYear W30234961662022 @default.
• W3023496166 countsByYear W30234961662023 @default.
• W3023496166 crossrefType "journal-article" @default.
• W3023496166 hasAuthorship W3023496166A5005756615 @default.
• W3023496166 hasAuthorship W3023496166A5007053229 @default.
• W3023496166 hasAuthorship W3023496166A5030352385 @default.
• W3023496166 hasAuthorship W3023496166A5053495030 @default.
• W3023496166 hasAuthorship W3023496166A5057296536 @default.
• W3023496166 hasConcept C108215921 @default.
• W3023496166 hasConcept C112613896 @default.
• W3023496166 hasConcept C11432220 @default.
• W3023496166 hasConcept C121332964 @default.
• W3023496166 hasConcept C12554922 @default.
• W3023496166 hasConcept C127413603 @default.
• W3023496166 hasConcept C13965031 @default.
• W3023496166 hasConcept C14631669 @default.
• W3023496166 hasConcept C150903083 @default.
• W3023496166 hasConcept C155672457 @default.
• W3023496166 hasConcept C160892712 @default.
• W3023496166 hasConcept C171250308 @default.
• W3023496166 hasConcept C178790620 @default.
• W3023496166 hasConcept C181389837 @default.
• W3023496166 hasConcept C185592680 @default.
• W3023496166 hasConcept C192562407 @default.
• W3023496166 hasConcept C207001950 @default.
• W3023496166 hasConcept C2778250585 @default.
• W3023496166 hasConcept C39519442 @default.
• W3023496166 hasConcept C42360764 @default.
• W3023496166 hasConcept C43617362 @default.
• W3023496166 hasConcept C521977710 @default.
• W3023496166 hasConcept C55493867 @default.
• W3023496166 hasConcept C71924100 @default.
• W3023496166 hasConcept C86803240 @default.
• W3023496166 hasConcept C86807702 @default.
• W3023496166 hasConcept C97355855 @default.
• W3023496166 hasConcept C98274493 @default.
• W3023496166 hasConceptScore W3023496166C108215921 @default.
• W3023496166 hasConceptScore W3023496166C112613896 @default.
• W3023496166 hasConceptScore W3023496166C11432220 @default.
• W3023496166 hasConceptScore W3023496166C121332964 @default.
• W3023496166 hasConceptScore W3023496166C12554922 @default.
• W3023496166 hasConceptScore W3023496166C127413603 @default.
• W3023496166 hasConceptScore W3023496166C13965031 @default.
• W3023496166 hasConceptScore W3023496166C14631669 @default.
• W3023496166 hasConceptScore W3023496166C150903083 @default.

• next