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- W3023562570 abstract "We thank Drs. Thiwari and Kumar for their interest 1 Thiwari Lokesh Kumar M. Oral prednisolone versus intramuscular corticotropin in West syndrome. Pediatr Neurol. 2016; 64 (e7) Google Scholar on our two recent publications related to our randomized single-blind clinical trial conducted to describe the electroencephalographic (EEG) outcome 2 Wanigasinghe J. Arambepola C. Sri Ranganathan S. Sumanasena S. Muhandiram E. The efficacy of moderate-to-high dose oral prednisolone versus low-to-moderate dose intramuscular corticotropin for improvement of hypsarrhythmia in west syndrome: a randomized, single-line, parallel clinical trial. Pediatr Neurol. 2014; 51: 24-30 Abstract Full Text Full Text PDF PubMed Scopus (34) Google Scholar and the immediate- and short-term spasm outcome 3 Wanigasinghe J. Arambepola C. Sri Ranganathan S. Sumanasena S. Attanapola G. Randomized, single-blind, parallel clinical trial on efficacy of oral prednisolone versus intramuscular corticotropin on immediate and continued spasm control in West syndrome. Pediatr Neurol. 2015; 53: 193-199 Abstract Full Text Full Text PDF PubMed Scopus (54) Google Scholar in children with West syndrome when treated with oral prednisolone versus intramuscular adrenocorticotropic hormone. We have tried to clarify the main points raised in their letter below. Oral Prednisolone Versus Intramuscular Corticotropin in West SyndromePediatric NeurologyVol. 64PreviewWest syndrome is a catastrophic and common epileptic syndrome. There are lots of uncertainties and consequent differences in treatment protocols for West syndrome arising from a paucity of scientific evidence1 especially with regards to first-line agents, i.e., corticosteroids versus adrenocorticotropic hormone versus vigabatrin. The familiarity of usage, easy availability, and inexpensive nature of prednisolone is lucrative especially for physicians working in underserved regions of developing economies. Full-Text PDF" @default.
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- W3023562570 date "2017-09-01" @default.
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- W3023562570 title "Letter Reply" @default.
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- W3023562570 doi "https://doi.org/10.1016/j.pediatrneurol.2016.04.005" @default.
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