FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3023590933> ?p ?o ?g. }

• W3023590933 endingPage "060802052515023" @default.
• W3023590933 startingPage "060802052515023" @default.
• W3023590933 abstract "Introduction: Tendon ruptures are increasingly common, repair can be difficult and healing poorly understood. Tissue engineering approaches often require expansion of cell numbers to populate a construct, and maintenance of cell phenotoype is essential for tissue regeneration. Methods: In this study we characterise the phenotype of human Achilles tenocytes and assess how this is affected by passaging. Tenocytes, isolated from tendon samples from 6 patients receiving surgery for rupture of the Achilles tendon, were passaged 8 times. Proliferation rates and cell morphology were recorded at passages 1, 4 and 8. Total collagen, the ratio of collagen types I and III and decorin were used as indicators of matrix formation and expression of the integrin ‘alpha’1 subunit as a marker of cell-matrix interactions. Results: With increasing passage number, cells became more rounded, were more widely spaced at confluence and confluent cell density declined from 18700 /cm2 to 16100 /cm2 (P=0.009). No change to total cell layer collagen was observed but the ratio of type III to type I collagen increased from 0.60 at passage 1 to 0.89 at passage 8 (P Conclusion: We conclude that the phenotype of tenocytes in culture rapidly drifts with progressive passage." @default.
• W3023590933 created "2020-05-13" @default.
• W3023590933 creator A5000096352 @default.
• W3023590933 creator A5024159880 @default.
• W3023590933 creator A5047656886 @default.
• W3023590933 creator A5080846643 @default.
• W3023590933 creator A5085505714 @default.
• W3023590933 date "2006-05-30" @default.
• W3023590933 modified "2023-09-27" @default.
• W3023590933 title "Phenotypic Drift in Human Tenocyte Culture" @default.
• W3023590933 cites W1543809841 @default.
• W3023590933 cites W1558943498 @default.
• W3023590933 cites W1563248949 @default.
• W3023590933 cites W1864154040 @default.
• W3023590933 cites W1921978279 @default.
• W3023590933 cites W1967127058 @default.
• W3023590933 cites W1968803649 @default.
• W3023590933 cites W1984908593 @default.
• W3023590933 cites W1985666624 @default.
• W3023590933 cites W1986391515 @default.
• W3023590933 cites W1993251840 @default.
• W3023590933 cites W2006977892 @default.
• W3023590933 cites W2012012268 @default.
• W3023590933 cites W2012650330 @default.
• W3023590933 cites W2015996457 @default.
• W3023590933 cites W2018882303 @default.
• W3023590933 cites W2033162091 @default.
• W3023590933 cites W2035258744 @default.
• W3023590933 cites W2036647753 @default.
• W3023590933 cites W2044788719 @default.
• W3023590933 cites W2052686525 @default.
• W3023590933 cites W2058538647 @default.
• W3023590933 cites W2075635582 @default.
• W3023590933 cites W2081854922 @default.
• W3023590933 cites W2084252373 @default.
• W3023590933 cites W2090326664 @default.
• W3023590933 cites W2103641779 @default.
• W3023590933 cites W2110962885 @default.
• W3023590933 cites W2116444049 @default.
• W3023590933 cites W2131687641 @default.
• W3023590933 cites W2138263364 @default.
• W3023590933 cites W2138941270 @default.
• W3023590933 cites W2151621078 @default.
• W3023590933 cites W2155852753 @default.
• W3023590933 cites W4213141530 @default.
• W3023590933 cites W4232671899 @default.
• W3023590933 doi "https://doi.org/10.1089/ten.2006.12.ft-90" @default.
• W3023590933 hasPublicationYear "2006" @default.
• W3023590933 type Work @default.
• W3023590933 sameAs 3023590933 @default.
• W3023590933 citedByCount "1" @default.
• W3023590933 countsByYear W30235909332019 @default.
• W3023590933 crossrefType "journal-article" @default.
• W3023590933 hasAuthorship W3023590933A5000096352 @default.
• W3023590933 hasAuthorship W3023590933A5024159880 @default.
• W3023590933 hasAuthorship W3023590933A5047656886 @default.
• W3023590933 hasAuthorship W3023590933A5080846643 @default.
• W3023590933 hasAuthorship W3023590933A5085505714 @default.
• W3023590933 hasConcept C104317684 @default.
• W3023590933 hasConcept C106487976 @default.
• W3023590933 hasConcept C127716648 @default.
• W3023590933 hasConcept C136229726 @default.
• W3023590933 hasConcept C142724271 @default.
• W3023590933 hasConcept C1491633281 @default.
• W3023590933 hasConcept C171056886 @default.
• W3023590933 hasConcept C185592680 @default.
• W3023590933 hasConcept C189165786 @default.
• W3023590933 hasConcept C195687474 @default.
• W3023590933 hasConcept C2779335624 @default.
• W3023590933 hasConcept C2779794767 @default.
• W3023590933 hasConcept C2780105995 @default.
• W3023590933 hasConcept C2780644872 @default.
• W3023590933 hasConcept C2780984734 @default.
• W3023590933 hasConcept C43617362 @default.
• W3023590933 hasConcept C49892992 @default.
• W3023590933 hasConcept C55493867 @default.
• W3023590933 hasConcept C71924100 @default.
• W3023590933 hasConcept C86803240 @default.
• W3023590933 hasConcept C95444343 @default.
• W3023590933 hasConceptScore W3023590933C104317684 @default.
• W3023590933 hasConceptScore W3023590933C106487976 @default.
• W3023590933 hasConceptScore W3023590933C127716648 @default.
• W3023590933 hasConceptScore W3023590933C136229726 @default.
• W3023590933 hasConceptScore W3023590933C142724271 @default.
• W3023590933 hasConceptScore W3023590933C1491633281 @default.
• W3023590933 hasConceptScore W3023590933C171056886 @default.
• W3023590933 hasConceptScore W3023590933C185592680 @default.
• W3023590933 hasConceptScore W3023590933C189165786 @default.
• W3023590933 hasConceptScore W3023590933C195687474 @default.
• W3023590933 hasConceptScore W3023590933C2779335624 @default.
• W3023590933 hasConceptScore W3023590933C2779794767 @default.
• W3023590933 hasConceptScore W3023590933C2780105995 @default.
• W3023590933 hasConceptScore W3023590933C2780644872 @default.
• W3023590933 hasConceptScore W3023590933C2780984734 @default.
• W3023590933 hasConceptScore W3023590933C43617362 @default.
• W3023590933 hasConceptScore W3023590933C49892992 @default.
• W3023590933 hasConceptScore W3023590933C55493867 @default.
• W3023590933 hasConceptScore W3023590933C71924100 @default.

• next