FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3023909096> ?p ?o ?g. }

• W3023909096 endingPage "482" @default.
• W3023909096 startingPage "482" @default.
• W3023909096 abstract "Gene expression regulation is achieved through an intricate network of molecular interactions, in which trans-acting transcription factors (TFs) and small noncoding RNAs (sncRNAs), including microRNAs (miRNAs) and PIWI-interacting RNAs (piRNAs), play a key role. Recent observations allowed postulating an interplay between TFs and sncRNAs, in that they may possibly share DNA-binding sites. The aim of this study was to analyze the complete subset of miRNA and piRNA sequences stored in the main databases in order to identify the occurrence of conserved motifs and subsequently predict a possible innovative interplay with TFs at a transcriptional level. To this aim, we adopted an original in silico workflow to search motifs and predict interactions within genome-scale regulatory networks. Our results allowed categorizing miRNA and piRNA motifs, with corresponding TFs sharing complementary DNA-binding motifs. The biological interpretation of the gene ontologies of the TFs permitted observing a selective enrichment in developmental pathways, allowing the distribution of miRNA motifs along a topological and chronological frame. In addition, piRNA motifs were categorized for the first time and revealed specific functional implications in somatic tissues. These data might pose experimental hypotheses to be tested in biological models, towards clarifying novel in gene regulatory routes." @default.
• W3023909096 created "2020-05-13" @default.
• W3023909096 creator A5001323477 @default.
• W3023909096 creator A5023355753 @default.
• W3023909096 creator A5054356543 @default.
• W3023909096 creator A5066648635 @default.
• W3023909096 date "2020-04-29" @default.
• W3023909096 modified "2023-10-03" @default.
• W3023909096 title "Rising Roles of Small Noncoding RNAs in Cotranscriptional Regulation: In Silico Study of miRNA and piRNA Regulatory Network in Humans" @default.
• W3023909096 cites W1912095687 @default.
• W3023909096 cites W1968629278 @default.
• W3023909096 cites W1972353480 @default.
• W3023909096 cites W1981509058 @default.
• W3023909096 cites W1985213868 @default.
• W3023909096 cites W1992696908 @default.
• W3023909096 cites W1998734533 @default.
• W3023909096 cites W2004714181 @default.
• W3023909096 cites W2011813973 @default.
• W3023909096 cites W2017426710 @default.
• W3023909096 cites W2024412145 @default.
• W3023909096 cites W2050110866 @default.
• W3023909096 cites W2066298061 @default.
• W3023909096 cites W2069009920 @default.
• W3023909096 cites W2077879161 @default.
• W3023909096 cites W2080423827 @default.
• W3023909096 cites W2092261551 @default.
• W3023909096 cites W2097175728 @default.
• W3023909096 cites W2103777723 @default.
• W3023909096 cites W2106637741 @default.
• W3023909096 cites W2106706219 @default.
• W3023909096 cites W2142878546 @default.
• W3023909096 cites W2153330772 @default.
• W3023909096 cites W2170952313 @default.
• W3023909096 cites W2234681847 @default.
• W3023909096 cites W2261001639 @default.
• W3023909096 cites W2291743740 @default.
• W3023909096 cites W2530597079 @default.
• W3023909096 cites W2591634521 @default.
• W3023909096 cites W2623559001 @default.
• W3023909096 cites W2748344419 @default.
• W3023909096 cites W2748994551 @default.
• W3023909096 cites W2770178180 @default.
• W3023909096 cites W2774855547 @default.
• W3023909096 cites W2806593469 @default.
• W3023909096 cites W2810270044 @default.
• W3023909096 cites W2811423273 @default.
• W3023909096 cites W2912031480 @default.
• W3023909096 cites W2921291120 @default.
• W3023909096 cites W2948393771 @default.
• W3023909096 cites W2948495288 @default.
• W3023909096 cites W2955943625 @default.
• W3023909096 cites W2958912017 @default.
• W3023909096 cites W2970244424 @default.
• W3023909096 cites W749191146 @default.
• W3023909096 doi "https://doi.org/10.3390/genes11050482" @default.
• W3023909096 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7290514" @default.
• W3023909096 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32365489" @default.
• W3023909096 hasPublicationYear "2020" @default.
• W3023909096 type Work @default.
• W3023909096 sameAs 3023909096 @default.
• W3023909096 citedByCount "8" @default.
• W3023909096 countsByYear W30239090962020 @default.
• W3023909096 countsByYear W30239090962021 @default.
• W3023909096 countsByYear W30239090962022 @default.
• W3023909096 countsByYear W30239090962023 @default.
• W3023909096 crossrefType "journal-article" @default.
• W3023909096 hasAuthorship W3023909096A5001323477 @default.
• W3023909096 hasAuthorship W3023909096A5023355753 @default.
• W3023909096 hasAuthorship W3023909096A5054356543 @default.
• W3023909096 hasAuthorship W3023909096A5066648635 @default.
• W3023909096 hasBestOaLocation W30239090961 @default.
• W3023909096 hasConcept C104317684 @default.
• W3023909096 hasConcept C141231307 @default.
• W3023909096 hasConcept C145059251 @default.
• W3023909096 hasConcept C147724379 @default.
• W3023909096 hasConcept C150194340 @default.
• W3023909096 hasConcept C165864922 @default.
• W3023909096 hasConcept C2775905019 @default.
• W3023909096 hasConcept C4918238 @default.
• W3023909096 hasConcept C54355233 @default.
• W3023909096 hasConcept C67339327 @default.
• W3023909096 hasConcept C70721500 @default.
• W3023909096 hasConcept C86339819 @default.
• W3023909096 hasConcept C86803240 @default.
• W3023909096 hasConceptScore W3023909096C104317684 @default.
• W3023909096 hasConceptScore W3023909096C141231307 @default.
• W3023909096 hasConceptScore W3023909096C145059251 @default.
• W3023909096 hasConceptScore W3023909096C147724379 @default.
• W3023909096 hasConceptScore W3023909096C150194340 @default.
• W3023909096 hasConceptScore W3023909096C165864922 @default.
• W3023909096 hasConceptScore W3023909096C2775905019 @default.
• W3023909096 hasConceptScore W3023909096C4918238 @default.
• W3023909096 hasConceptScore W3023909096C54355233 @default.
• W3023909096 hasConceptScore W3023909096C67339327 @default.
• W3023909096 hasConceptScore W3023909096C70721500 @default.
• W3023909096 hasConceptScore W3023909096C86339819 @default.
• W3023909096 hasConceptScore W3023909096C86803240 @default.
• W3023909096 hasIssue "5" @default.

• next