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- W3023933198 abstract "Background The only HIV pre-exposure prophylaxis (PrEP) regimen approved in Australia is daily co-formulated tenofovir and emtricitabine. As an alternative, on-demand PrEP could offer benefits, including lower pill burden for people having sex infrequently. We surveyed PrEPX study participants to measure interest in switching from daily PrEP to on-demand PrEP. Methods The survey asked 15 questions on demographics, sexual behaviour, interest in on-demand PrEP, and reasons for interest. Univariate regression analyses assessed associations between interest in on-demand PrEP and other survey questions, and questions with significant (p Results 970 responses were complete. Respondents’ median age was 39 years, and 99.6% were male. All had taken daily PrEP, but 14% had ceased PrEP. 469 respondents (48%; 95%CI 45–52) reported interest in on-demand PrEP. In multivariate analysis, interest in on-demand PrEP was independently associated with having ceased PrEP (aOR 2.0, p Conclusion This is the first study of interest in switching from daily to on-demand PrEP. Half of respondents were interested, and interest was most strongly associated with infrequency of sex and concerns about long-term toxicity. However, many respondents had concerns about the effectiveness of on-demand PrEP, and about forgetting to take on-demand PrEP at least two hours before sex. Disclosure No significant relationships." @default.
- W3023933198 created "2020-05-13" @default.
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- W3023933198 date "2019-07-01" @default.
- W3023933198 modified "2023-09-24" @default.
- W3023933198 title "P430 Predictors of interest in switching from daily to on-demand HIV Pre-Exposure Prophylaxis (PrEP) among australians" @default.
- W3023933198 doi "https://doi.org/10.1136/sextrans-2019-sti.516" @default.
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