FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024011475> ?p ?o ?g. }

• W3024011475 endingPage "877" @default.
• W3024011475 startingPage "871" @default.
• W3024011475 abstract "Abstract First inspired by the seminal work of Lewontin and Krakauer (1973. Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms. Genetics 74(1):175–195.) and Maynard Smith and Haigh (1974. The hitch-hiking effect of a favourable gene. Genet Res. 23(1):23–35.), genomic scans for positive selection remain a widely utilized tool in modern population genomic analysis. Yet, the relative frequency and genomic impact of selective sweeps have remained a contentious point in the field for decades, largely owing to an inability to accurately identify their presence and quantify their effects—with current methodologies generally being characterized by low true-positive rates and/or high false-positive rates under many realistic demographic models. Most of these approaches are based on Wright–Fisher assumptions and the Kingman coalescent and generally rely on detecting outlier regions which do not conform to these neutral expectations. However, previous theoretical results have demonstrated that selective sweeps are well characterized by an alternative class of model known as the multiple-merger coalescent. Taken together, this suggests the possibility of not simply identifying regions which reject the Kingman, but rather explicitly testing the relative fit of a genomic window to the multiple-merger coalescent. We describe the advantages of such an approach, which owe to the branching structure differentiating selective and neutral models, and demonstrate improved power under certain demographic scenarios relative to a commonly used approach. However, regions of the demographic parameter space continue to exist in which neither this approach nor existing methodologies have sufficient power to detect selective sweeps." @default.
• W3024011475 created "2020-05-21" @default.
• W3024011475 creator A5020301143 @default.
• W3024011475 creator A5026037748 @default.
• W3024011475 date "2020-05-12" @default.
• W3024011475 modified "2023-10-11" @default.
• W3024011475 title "Considering Genomic Scans for Selection as Coalescent Model Choice" @default.
• W3024011475 cites W1627352199 @default.
• W3024011475 cites W1980804579 @default.
• W3024011475 cites W2016145816 @default.
• W3024011475 cites W2069672194 @default.
• W3024011475 cites W2093373663 @default.
• W3024011475 cites W2099938953 @default.
• W3024011475 cites W2102951980 @default.
• W3024011475 cites W2103286878 @default.
• W3024011475 cites W2109183238 @default.
• W3024011475 cites W2109195195 @default.
• W3024011475 cites W2111699978 @default.
• W3024011475 cites W2116346080 @default.
• W3024011475 cites W2116668053 @default.
• W3024011475 cites W2122510797 @default.
• W3024011475 cites W2124165778 @default.
• W3024011475 cites W2124653005 @default.
• W3024011475 cites W2156169823 @default.
• W3024011475 cites W2156886335 @default.
• W3024011475 cites W2163223875 @default.
• W3024011475 cites W2163958331 @default.
• W3024011475 cites W2165974744 @default.
• W3024011475 cites W2171463101 @default.
• W3024011475 cites W2172569011 @default.
• W3024011475 cites W2291016016 @default.
• W3024011475 cites W2766773217 @default.
• W3024011475 cites W2896260141 @default.
• W3024011475 cites W2901659912 @default.
• W3024011475 cites W2950215359 @default.
• W3024011475 cites W2951309130 @default.
• W3024011475 cites W2951621382 @default.
• W3024011475 cites W2951697196 @default.
• W3024011475 cites W4210633230 @default.
• W3024011475 cites W4234059023 @default.
• W3024011475 cites W4251304755 @default.
• W3024011475 doi "https://doi.org/10.1093/gbe/evaa093" @default.
• W3024011475 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7313662" @default.
• W3024011475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32396636" @default.
• W3024011475 hasPublicationYear "2020" @default.
• W3024011475 type Work @default.
• W3024011475 sameAs 3024011475 @default.
• W3024011475 citedByCount "8" @default.
• W3024011475 countsByYear W30240114752021 @default.
• W3024011475 countsByYear W30240114752022 @default.
• W3024011475 countsByYear W30240114752023 @default.
• W3024011475 crossrefType "journal-article" @default.
• W3024011475 hasAuthorship W3024011475A5020301143 @default.
• W3024011475 hasAuthorship W3024011475A5026037748 @default.
• W3024011475 hasBestOaLocation W30240114751 @default.
• W3024011475 hasConcept C104317684 @default.
• W3024011475 hasConcept C105795698 @default.
• W3024011475 hasConcept C119857082 @default.
• W3024011475 hasConcept C141231307 @default.
• W3024011475 hasConcept C144024400 @default.
• W3024011475 hasConcept C149782125 @default.
• W3024011475 hasConcept C149923435 @default.
• W3024011475 hasConcept C151730666 @default.
• W3024011475 hasConcept C1570309 @default.
• W3024011475 hasConcept C199360897 @default.
• W3024011475 hasConcept C2554327 @default.
• W3024011475 hasConcept C2776620128 @default.
• W3024011475 hasConcept C2777667586 @default.
• W3024011475 hasConcept C2779343474 @default.
• W3024011475 hasConcept C2779377595 @default.
• W3024011475 hasConcept C2908647359 @default.
• W3024011475 hasConcept C33923547 @default.
• W3024011475 hasConcept C41008148 @default.
• W3024011475 hasConcept C54355233 @default.
• W3024011475 hasConcept C7386963 @default.
• W3024011475 hasConcept C78458016 @default.
• W3024011475 hasConcept C79337645 @default.
• W3024011475 hasConcept C81917197 @default.
• W3024011475 hasConcept C85721925 @default.
• W3024011475 hasConcept C86803240 @default.
• W3024011475 hasConcept C90132467 @default.
• W3024011475 hasConceptScore W3024011475C104317684 @default.
• W3024011475 hasConceptScore W3024011475C105795698 @default.
• W3024011475 hasConceptScore W3024011475C119857082 @default.
• W3024011475 hasConceptScore W3024011475C141231307 @default.
• W3024011475 hasConceptScore W3024011475C144024400 @default.
• W3024011475 hasConceptScore W3024011475C149782125 @default.
• W3024011475 hasConceptScore W3024011475C149923435 @default.
• W3024011475 hasConceptScore W3024011475C151730666 @default.
• W3024011475 hasConceptScore W3024011475C1570309 @default.
• W3024011475 hasConceptScore W3024011475C199360897 @default.
• W3024011475 hasConceptScore W3024011475C2554327 @default.
• W3024011475 hasConceptScore W3024011475C2776620128 @default.
• W3024011475 hasConceptScore W3024011475C2777667586 @default.
• W3024011475 hasConceptScore W3024011475C2779343474 @default.
• W3024011475 hasConceptScore W3024011475C2779377595 @default.
• W3024011475 hasConceptScore W3024011475C2908647359 @default.
• W3024011475 hasConceptScore W3024011475C33923547 @default.

• next