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- W3024085422 abstract "ABSTRACT MutantHuntWGS is a user-friendly pipeline for analyzing Saccharomyces cerevisiae whole-genome sequencing data. It uses available open-source programs to: (1) perform sequence alignments for paired and single-end reads, (2) call variants, and (3) predict variant effect and severity. MutantHuntWGS outputs a shortlist of variants while also enabling access to all intermediate files. To demonstrate its utility, we use MutantHuntWGS to assess multiple published datasets; in all cases, it detects the same causal variants reported in the literature. To encourage broad adoption and promote reproducibility, we distribute a containerized version of the MutantHuntWGS pipeline that allows users to install and analyze data with only two commands. The MutantHuntWGS software and documentation can be downloaded free of charge from https://github.com/mae92/MutantHuntWGS ." @default.
- W3024085422 created "2020-05-21" @default.
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- W3024085422 date "2020-05-17" @default.
- W3024085422 modified "2023-10-17" @default.
- W3024085422 title "MutantHuntWGS: A Pipeline for Identifying Saccharomyces cerevisiae Mutations" @default.
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- W3024085422 doi "https://doi.org/10.1101/2020.05.16.099259" @default.
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