Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024114689> ?p ?o ?g. }
- W3024114689 endingPage "034009" @default.
- W3024114689 startingPage "034009" @default.
- W3024114689 abstract "Abstract Carbon-based materials (CBMs), such as graphene, nanodiamonds, carbon fibers, and carbon dots, have attracted a great deal scientific attention due to their potential as biomedical tools. Following exposure, particularly intravenous injection, these nanomaterials can be recognized by immune cells. Such interactions could be modulated by the different physicochemical properties of the materials (e.g. structure, size, and chemical functions), by either stimulating or suppressing the immune response. However, a harmonized cutting-edge approach for the classification of these materials based not only on their physicochemical parameters but also their immune properties has been missing. The European Commission-funded G-IMMUNOMICS and CARBO-IMmap projects aimed to fill this gap, developing a functional pipeline for the qualitative and quantitative immune characterization of graphene, graphene-related materials (GRMs), and other CBMs. The goal was to open breakthrough perspectives for the definition of the immune profiles of these materials. Here, we summarize our methodological approach, key results, and the necessary multidisciplinary expertise ranging across various fields, from material chemistry to engineering, immunology, toxicology, and systems biology. G-IMMUNOMICS, as a partnering project of the Graphene Flagship, the largest scientific research initiative on graphene worldwide, also complemented the studies performed in the Flagship on health and environmental impact of GRMs. Finally, we present the nanoimmunity-by-design concept, developed within the projects, which can be readily applied to other 2D materials. Overall, the G-IMMUNOMICS and CARBO-IMmap projects have provided new insights on the immune impact of GRMs and CBMs, thus laying the foundation for their safe use and future translation in medicine." @default.
- W3024114689 created "2020-05-21" @default.
- W3024114689 creator A5000038132 @default.
- W3024114689 creator A5000517481 @default.
- W3024114689 creator A5001995594 @default.
- W3024114689 creator A5002791537 @default.
- W3024114689 creator A5003243714 @default.
- W3024114689 creator A5011436623 @default.
- W3024114689 creator A5016841692 @default.
- W3024114689 creator A5017462048 @default.
- W3024114689 creator A5018823387 @default.
- W3024114689 creator A5022401273 @default.
- W3024114689 creator A5035381852 @default.
- W3024114689 creator A5038531227 @default.
- W3024114689 creator A5040127886 @default.
- W3024114689 creator A5040150221 @default.
- W3024114689 creator A5040839915 @default.
- W3024114689 creator A5041756883 @default.
- W3024114689 creator A5044514703 @default.
- W3024114689 creator A5047441212 @default.
- W3024114689 creator A5054507368 @default.
- W3024114689 creator A5056755521 @default.
- W3024114689 creator A5057165591 @default.
- W3024114689 creator A5061122191 @default.
- W3024114689 creator A5061903235 @default.
- W3024114689 creator A5062040602 @default.
- W3024114689 creator A5063131791 @default.
- W3024114689 creator A5063883723 @default.
- W3024114689 creator A5064740851 @default.
- W3024114689 creator A5068431848 @default.
- W3024114689 creator A5071591293 @default.
- W3024114689 creator A5074191348 @default.
- W3024114689 creator A5075018791 @default.
- W3024114689 creator A5079147001 @default.
- W3024114689 creator A5081386207 @default.
- W3024114689 date "2020-07-01" @default.
- W3024114689 modified "2023-10-11" @default.
- W3024114689 title "Graphene, other carbon nanomaterials and the immune system: toward nanoimmunity-by-design" @default.
- W3024114689 cites W1671034959 @default.
- W3024114689 cites W1779863323 @default.
- W3024114689 cites W1876014280 @default.
- W3024114689 cites W1976209715 @default.
- W3024114689 cites W1988871238 @default.
- W3024114689 cites W1992881751 @default.
- W3024114689 cites W1995234326 @default.
- W3024114689 cites W1997288069 @default.
- W3024114689 cites W1997878371 @default.
- W3024114689 cites W2006729360 @default.
- W3024114689 cites W2011370572 @default.
- W3024114689 cites W2020790894 @default.
- W3024114689 cites W2028207904 @default.
- W3024114689 cites W2029057348 @default.
- W3024114689 cites W2034137394 @default.
- W3024114689 cites W2036166803 @default.
- W3024114689 cites W2052971899 @default.
- W3024114689 cites W2058122340 @default.
- W3024114689 cites W2078792724 @default.
- W3024114689 cites W2080516615 @default.
- W3024114689 cites W2084211225 @default.
- W3024114689 cites W2084630938 @default.
- W3024114689 cites W2094033379 @default.
- W3024114689 cites W2095530118 @default.
- W3024114689 cites W2098565706 @default.
- W3024114689 cites W2100788147 @default.
- W3024114689 cites W2111163976 @default.
- W3024114689 cites W2122314640 @default.
- W3024114689 cites W2124811111 @default.
- W3024114689 cites W2129906907 @default.
- W3024114689 cites W2132112416 @default.
- W3024114689 cites W2136899243 @default.
- W3024114689 cites W2138003976 @default.
- W3024114689 cites W2142129168 @default.
- W3024114689 cites W2142833210 @default.
- W3024114689 cites W2145237811 @default.
- W3024114689 cites W2145391404 @default.
- W3024114689 cites W2151609134 @default.
- W3024114689 cites W2158884438 @default.
- W3024114689 cites W2163980958 @default.
- W3024114689 cites W2204694633 @default.
- W3024114689 cites W2216723571 @default.
- W3024114689 cites W2257458640 @default.
- W3024114689 cites W2261475005 @default.
- W3024114689 cites W2278924796 @default.
- W3024114689 cites W2312212049 @default.
- W3024114689 cites W2320766206 @default.
- W3024114689 cites W2401972049 @default.
- W3024114689 cites W2407562350 @default.
- W3024114689 cites W2409248716 @default.
- W3024114689 cites W2495358084 @default.
- W3024114689 cites W2517028335 @default.
- W3024114689 cites W2531341616 @default.
- W3024114689 cites W2543922278 @default.
- W3024114689 cites W2585660514 @default.
- W3024114689 cites W2586976801 @default.
- W3024114689 cites W2597201781 @default.
- W3024114689 cites W2600903649 @default.
- W3024114689 cites W2604206885 @default.
- W3024114689 cites W2607389452 @default.