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- W30241777 abstract "Controlled studies on the immunopathogenesis of mucosal candidiasis in HIV infection have been hampered by the lack of a relevant animal model. We have previously reported that oral Candida infection in CD4C/HIV transgenic mice expressing gene products of HIV-1 in immune cells and developing an AIDS-like disease closely mimics oropharyngeal candidiasis in human HIV infection. The role of defective dendritic cells and CD4+ T cells in impaired induction of protective immunity and in the phenotype of chronic oral carriage of C. albicans can now be investigated under controlled conditions in these transgenic mice." @default.
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- W30241777 date "2009-01-01" @default.
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- W30241777 title "Oral Mucosal Cell Response to Candida albicans in Transgenic Mice Expressing HIV-1" @default.
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- W30241777 doi "https://doi.org/10.1007/978-1-59745-204-5_25" @default.
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