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- W3024195440 abstract "The cell surface is a mechanobiological unit that encompasses the plasma membrane, its interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been directed to the mechanics of the plasma membrane, and in particular membrane tension, which has been linked to diverse cellular processes such as cell migration and membrane trafficking. However, how tension across the plasma membrane is regulated and propagated is still not completely understood. Here, we review recent efforts to study the interplay between membrane tension and the cytoskeletal machinery and how they control cell form and function. We focus on factors that have been proposed to affect the propagation of membrane tension and as such could determine whether it can act as a global or local regulator of cell behavior. Finally, we discuss the limitations of the available tool kit as new approaches that reveal its dynamics in cells are needed to decipher how membrane tension regulates diverse cellular processes." @default.
- W3024195440 created "2020-05-21" @default.
- W3024195440 creator A5023743425 @default.
- W3024195440 creator A5082228969 @default.
- W3024195440 date "2020-10-01" @default.
- W3024195440 modified "2023-10-17" @default.
- W3024195440 title "Pay attention to membrane tension: Mechanobiology of the cell surface" @default.
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- W3024195440 doi "https://doi.org/10.1016/j.ceb.2020.04.001" @default.
- W3024195440 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7594640" @default.
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