Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024233105> ?p ?o ?g. }
- W3024233105 endingPage "517" @default.
- W3024233105 startingPage "512" @default.
- W3024233105 abstract "Systemic methotrexate (MTX) is a useful treatment for many dermatologic conditions, however, the risk of adverse events prevents its use in patients with minimal or localized disease. Topical application of MTX may be an option to avoid the systemic adverse effects of oral MTX.To assess what is known about the efficacy and safety of topical methotrexate.A search on Pubmed was conducted. There were no limits on publication date.A total of 963 articles were discovered. Using our exclusion criteria, 916 articles were excluded; 47 articles were used for full text assessment. Topical MTX has been used primarily in psoriasis but also in mycosis fungoides, lymphomatoid papulosis, and oral precancerous lesions. Optimal delivery system and formulation for adequate penetration is still under investigation.The quality of evidence for the utility of topical methotrexate in psoriasis is good, however, for other dermatologic diseases, the quality is poor. Topical MTX with improved delivery methods may be a viable tool against certain localized dermatologic conditions for patients who do not tolerate oral MTX. Further double-blinded randomized controled studies are needed to substantiate the utility of topical methotrexate." @default.
- W3024233105 created "2020-05-21" @default.
- W3024233105 creator A5038667029 @default.
- W3024233105 creator A5045982906 @default.
- W3024233105 creator A5062008152 @default.
- W3024233105 creator A5089485688 @default.
- W3024233105 date "2020-05-25" @default.
- W3024233105 modified "2023-10-02" @default.
- W3024233105 title "Topical methotrexate in dermatology: a review of the literature" @default.
- W3024233105 cites W1881722651 @default.
- W3024233105 cites W190462675 @default.
- W3024233105 cites W1964219681 @default.
- W3024233105 cites W1967709592 @default.
- W3024233105 cites W1994030928 @default.
- W3024233105 cites W1998740541 @default.
- W3024233105 cites W2002250972 @default.
- W3024233105 cites W2010142221 @default.
- W3024233105 cites W2017942706 @default.
- W3024233105 cites W2021690910 @default.
- W3024233105 cites W2024862045 @default.
- W3024233105 cites W2037766236 @default.
- W3024233105 cites W2037864150 @default.
- W3024233105 cites W2046303682 @default.
- W3024233105 cites W2054435240 @default.
- W3024233105 cites W2057980339 @default.
- W3024233105 cites W2059107745 @default.
- W3024233105 cites W2076047218 @default.
- W3024233105 cites W2078168033 @default.
- W3024233105 cites W2079615220 @default.
- W3024233105 cites W2084928487 @default.
- W3024233105 cites W2086848741 @default.
- W3024233105 cites W2086895484 @default.
- W3024233105 cites W2090534400 @default.
- W3024233105 cites W2102254905 @default.
- W3024233105 cites W2113362782 @default.
- W3024233105 cites W2122917464 @default.
- W3024233105 cites W2128357711 @default.
- W3024233105 cites W2130835116 @default.
- W3024233105 cites W2133212411 @default.
- W3024233105 cites W2135168901 @default.
- W3024233105 cites W2138426564 @default.
- W3024233105 cites W2145989293 @default.
- W3024233105 cites W2162874779 @default.
- W3024233105 cites W2168504907 @default.
- W3024233105 cites W2275986086 @default.
- W3024233105 cites W2288226007 @default.
- W3024233105 cites W2404150437 @default.
- W3024233105 cites W2737629206 @default.
- W3024233105 cites W2760455169 @default.
- W3024233105 cites W2789388145 @default.
- W3024233105 cites W2891474673 @default.
- W3024233105 cites W2914029499 @default.
- W3024233105 cites W4256085234 @default.
- W3024233105 cites W787538427 @default.
- W3024233105 doi "https://doi.org/10.1080/09546634.2020.1770170" @default.
- W3024233105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32412810" @default.
- W3024233105 hasPublicationYear "2020" @default.
- W3024233105 type Work @default.
- W3024233105 sameAs 3024233105 @default.
- W3024233105 citedByCount "15" @default.
- W3024233105 countsByYear W30242331052020 @default.
- W3024233105 countsByYear W30242331052021 @default.
- W3024233105 countsByYear W30242331052022 @default.
- W3024233105 countsByYear W30242331052023 @default.
- W3024233105 crossrefType "journal-article" @default.
- W3024233105 hasAuthorship W3024233105A5038667029 @default.
- W3024233105 hasAuthorship W3024233105A5045982906 @default.
- W3024233105 hasAuthorship W3024233105A5062008152 @default.
- W3024233105 hasAuthorship W3024233105A5089485688 @default.
- W3024233105 hasBestOaLocation W30242331052 @default.
- W3024233105 hasConcept C118487528 @default.
- W3024233105 hasConcept C126322002 @default.
- W3024233105 hasConcept C141071460 @default.
- W3024233105 hasConcept C16005928 @default.
- W3024233105 hasConcept C197934379 @default.
- W3024233105 hasConcept C2777182591 @default.
- W3024233105 hasConcept C2777756187 @default.
- W3024233105 hasConcept C2778397455 @default.
- W3024233105 hasConcept C2778527774 @default.
- W3024233105 hasConcept C2779338263 @default.
- W3024233105 hasConcept C2779578545 @default.
- W3024233105 hasConcept C2780564577 @default.
- W3024233105 hasConcept C2781059491 @default.
- W3024233105 hasConcept C2781382166 @default.
- W3024233105 hasConcept C71924100 @default.
- W3024233105 hasConcept C98274493 @default.
- W3024233105 hasConceptScore W3024233105C118487528 @default.
- W3024233105 hasConceptScore W3024233105C126322002 @default.
- W3024233105 hasConceptScore W3024233105C141071460 @default.
- W3024233105 hasConceptScore W3024233105C16005928 @default.
- W3024233105 hasConceptScore W3024233105C197934379 @default.
- W3024233105 hasConceptScore W3024233105C2777182591 @default.
- W3024233105 hasConceptScore W3024233105C2777756187 @default.
- W3024233105 hasConceptScore W3024233105C2778397455 @default.
- W3024233105 hasConceptScore W3024233105C2778527774 @default.
- W3024233105 hasConceptScore W3024233105C2779338263 @default.
- W3024233105 hasConceptScore W3024233105C2779578545 @default.
- W3024233105 hasConceptScore W3024233105C2780564577 @default.