FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024254503> ?p ?o ?g. }

• W3024254503 endingPage "249" @default.
• W3024254503 startingPage "249" @default.
• W3024254503 abstract "The application of various isonitrile-based multicomponent reactions to protected (2-oxoethyl)boronic acid (as the carbonyl component) is described. The Ugi reaction, both in the four components and in the four centers–three components versions, and the van Leusen reaction, proved effective at providing small libraries of MIDA-protected β-aminoboronic acids. The corresponding free β-aminoboronic acids, quantitatively recovered through basic mild deprotection, were found to be quite stable and were fully characterized, including by 11B-NMR spectroscopy. Single-crystal X-ray diffraction analysis, applied both to a MIDA-protected and a free β-aminoboronic acid derivative, provided evidence for different conformations in the solid-state. Finally, the antimicrobial activities of selected compounds were evaluated by measuring their minimal inhibitory concentration (MIC) values, and the binding mode of the most promising derivative on OXA-23 class D β-lactamase was predicted by a molecular modeling study." @default.
• W3024254503 created "2020-05-21" @default.
• W3024254503 creator A5006711836 @default.
• W3024254503 creator A5010195258 @default.
• W3024254503 creator A5013096980 @default.
• W3024254503 creator A5026068230 @default.
• W3024254503 creator A5031979084 @default.
• W3024254503 creator A5036279485 @default.
• W3024254503 creator A5052684973 @default.
• W3024254503 creator A5067141747 @default.
• W3024254503 date "2020-05-12" @default.
• W3024254503 modified "2023-09-26" @default.
• W3024254503 title "Isonitrile-Based Multicomponent Synthesis of β-Amino Boronic Acids as β-Lactamase Inhibitors" @default.
• W3024254503 cites W1191097708 @default.
• W3024254503 cites W1918016093 @default.
• W3024254503 cites W1924841364 @default.
• W3024254503 cites W1955112614 @default.
• W3024254503 cites W1964529071 @default.
• W3024254503 cites W1966069936 @default.
• W3024254503 cites W1971186057 @default.
• W3024254503 cites W1976499671 @default.
• W3024254503 cites W1994588044 @default.
• W3024254503 cites W2002596407 @default.
• W3024254503 cites W2026392596 @default.
• W3024254503 cites W2029667189 @default.
• W3024254503 cites W2045087237 @default.
• W3024254503 cites W2079181493 @default.
• W3024254503 cites W2096885367 @default.
• W3024254503 cites W2097647469 @default.
• W3024254503 cites W2102377211 @default.
• W3024254503 cites W2132454074 @default.
• W3024254503 cites W2133776410 @default.
• W3024254503 cites W2153228625 @default.
• W3024254503 cites W2226714711 @default.
• W3024254503 cites W2260368947 @default.
• W3024254503 cites W2514862676 @default.
• W3024254503 cites W2515850068 @default.
• W3024254503 cites W2769066285 @default.
• W3024254503 cites W2770383775 @default.
• W3024254503 cites W2783692792 @default.
• W3024254503 cites W2797145650 @default.
• W3024254503 cites W2800459711 @default.
• W3024254503 cites W2912818999 @default.
• W3024254503 cites W2952401930 @default.
• W3024254503 cites W2953090724 @default.
• W3024254503 cites W2955791106 @default.
• W3024254503 cites W2982214079 @default.
• W3024254503 cites W2995120671 @default.
• W3024254503 doi "https://doi.org/10.3390/antibiotics9050249" @default.
• W3024254503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7277116" @default.
• W3024254503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32408714" @default.
• W3024254503 hasPublicationYear "2020" @default.
• W3024254503 type Work @default.
• W3024254503 sameAs 3024254503 @default.
• W3024254503 citedByCount "12" @default.
• W3024254503 countsByYear W30242545032020 @default.
• W3024254503 countsByYear W30242545032021 @default.
• W3024254503 countsByYear W30242545032022 @default.
• W3024254503 countsByYear W30242545032023 @default.
• W3024254503 crossrefType "journal-article" @default.
• W3024254503 hasAuthorship W3024254503A5006711836 @default.
• W3024254503 hasAuthorship W3024254503A5010195258 @default.
• W3024254503 hasAuthorship W3024254503A5013096980 @default.
• W3024254503 hasAuthorship W3024254503A5026068230 @default.
• W3024254503 hasAuthorship W3024254503A5031979084 @default.
• W3024254503 hasAuthorship W3024254503A5036279485 @default.
• W3024254503 hasAuthorship W3024254503A5052684973 @default.
• W3024254503 hasAuthorship W3024254503A5067141747 @default.
• W3024254503 hasBestOaLocation W30242545031 @default.
• W3024254503 hasConcept C106159729 @default.
• W3024254503 hasConcept C111771559 @default.
• W3024254503 hasConcept C162324750 @default.
• W3024254503 hasConcept C178910836 @default.
• W3024254503 hasConcept C185592680 @default.
• W3024254503 hasConcept C21951064 @default.
• W3024254503 hasConcept C2777864310 @default.
• W3024254503 hasConcept C515207424 @default.
• W3024254503 hasConcept C55493867 @default.
• W3024254503 hasConcept C66974803 @default.
• W3024254503 hasConcept C71240020 @default.
• W3024254503 hasConceptScore W3024254503C106159729 @default.
• W3024254503 hasConceptScore W3024254503C111771559 @default.
• W3024254503 hasConceptScore W3024254503C162324750 @default.
• W3024254503 hasConceptScore W3024254503C178910836 @default.
• W3024254503 hasConceptScore W3024254503C185592680 @default.
• W3024254503 hasConceptScore W3024254503C21951064 @default.
• W3024254503 hasConceptScore W3024254503C2777864310 @default.
• W3024254503 hasConceptScore W3024254503C515207424 @default.
• W3024254503 hasConceptScore W3024254503C55493867 @default.
• W3024254503 hasConceptScore W3024254503C66974803 @default.
• W3024254503 hasConceptScore W3024254503C71240020 @default.
• W3024254503 hasIssue "5" @default.
• W3024254503 hasLocation W30242545031 @default.
• W3024254503 hasLocation W30242545032 @default.
• W3024254503 hasLocation W30242545033 @default.
• W3024254503 hasLocation W30242545034 @default.
• W3024254503 hasLocation W30242545035 @default.
• W3024254503 hasLocation W30242545036 @default.

• next