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- W3024262723 endingPage "488" @default.
- W3024262723 startingPage "467" @default.
- W3024262723 abstract "The major impact produced by the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) focused many researchers attention to find treatments that can suppress transmission or ameliorate the disease. Despite the very fast and large flow of scientific data on possible treatment solutions, none have yet demonstrated unequivocal clinical utility against coronavirus disease 2019 (COVID‑19). This work represents an exhaustive and critical review of all available data on potential treatments for COVID‑19, highlighting their mechanistic characteristics and the strategy development rationale. Drug repurposing, also known as drug repositioning, and target based methods are the most used strategies to advance therapeutic solutions into clinical practice. Current in silico, in vitro and in vivo evidence regarding proposed treatments are summarized providing strong support for future research efforts." @default.
- W3024262723 created "2020-05-21" @default.
- W3024262723 creator A5013850053 @default.
- W3024262723 creator A5017338998 @default.
- W3024262723 creator A5019971065 @default.
- W3024262723 creator A5028661644 @default.
- W3024262723 creator A5035636294 @default.
- W3024262723 creator A5060727081 @default.
- W3024262723 creator A5073434880 @default.
- W3024262723 creator A5077451508 @default.
- W3024262723 creator A5079492560 @default.
- W3024262723 creator A5082686479 @default.
- W3024262723 date "2020-05-18" @default.
- W3024262723 modified "2023-10-18" @default.
- W3024262723 title "Comprehensive analysis of drugs to treat SARS‑CoV‑2 infection: Mechanistic insights into current COVID‑19 therapies (Review)" @default.
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