FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024321941> ?p ?o ?g. }

• W3024321941 endingPage "201" @default.
• W3024321941 startingPage "194" @default.
• W3024321941 abstract "Environmental enrichment items such as running wheels can promote the wellbeing of laboratory mice. Growing evidence suggests that wheel running simulates exercise effects in many mouse models of human conditions, but this activity also might change other aspects of mouse behavior. In this case study, we show that the presence of running wheels leads to pronounced and permanent circling behavior with route-tracing in a proportion of the male mice of a genetically distinct cohort. The genetic background of this cohort includes a mutation in Arhgap19, but genetic crosses showed that an unknown second-site mutation likely caused the induced circling behavior. Behavioral tests for inner-ear function indicated a normal sense of gravity in the circling mice. However, the levels of dopamine, serotonin, and some dopamine metabolites were lower in the brains of circling male mice than in mice of the same genetic background that were weaned without wheels. Circling was seen in both singly and socially housed male mice. The additional stress of fighting may have exacerbated the predisposition to circling in the socially housed animals. Singly and socially housed male mice without wheels did not circle. Our current findings highlight the importance and possibly confounding nature of the environmental and genetic background in mouse behavioral studies, given that the circling behavior and alterations in dopamine and serotonin levels in this mouse cohort occurred only when the male mice were housed with running wheels." @default.
• W3024321941 created "2020-05-21" @default.
• W3024321941 creator A5004102451 @default.
• W3024321941 creator A5031776620 @default.
• W3024321941 creator A5061668278 @default.
• W3024321941 creator A5088403251 @default.
• W3024321941 date "2017-03-01" @default.
• W3024321941 modified "2023-09-23" @default.
• W3024321941 title "What Goes Around Can Come Around: An Unexpected Deleterious Effect of Using Mouse Running Wheels for Environmental Enrichment." @default.
• W3024321941 cites W1061219605 @default.
• W3024321941 cites W1576927780 @default.
• W3024321941 cites W1931544284 @default.
• W3024321941 cites W1941119841 @default.
• W3024321941 cites W1964386825 @default.
• W3024321941 cites W1971624635 @default.
• W3024321941 cites W1976371997 @default.
• W3024321941 cites W1981428533 @default.
• W3024321941 cites W1983519246 @default.
• W3024321941 cites W1997575792 @default.
• W3024321941 cites W1998411467 @default.
• W3024321941 cites W2007608386 @default.
• W3024321941 cites W2008681552 @default.
• W3024321941 cites W2017527220 @default.
• W3024321941 cites W2020069888 @default.
• W3024321941 cites W2021488978 @default.
• W3024321941 cites W2026748077 @default.
• W3024321941 cites W2028378639 @default.
• W3024321941 cites W2029064513 @default.
• W3024321941 cites W2052358820 @default.
• W3024321941 cites W2070178859 @default.
• W3024321941 cites W2078345142 @default.
• W3024321941 cites W2082609535 @default.
• W3024321941 cites W2086635661 @default.
• W3024321941 cites W2094077228 @default.
• W3024321941 cites W2102633041 @default.
• W3024321941 cites W2103951116 @default.
• W3024321941 cites W2108312152 @default.
• W3024321941 cites W2108611459 @default.
• W3024321941 cites W2146019567 @default.
• W3024321941 cites W2148856395 @default.
• W3024321941 cites W2172674009 @default.
• W3024321941 cites W2182591962 @default.
• W3024321941 cites W2560416815 @default.
• W3024321941 cites W428070780 @default.
• W3024321941 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5361047" @default.
• W3024321941 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28315651" @default.
• W3024321941 hasPublicationYear "2017" @default.
• W3024321941 type Work @default.
• W3024321941 sameAs 3024321941 @default.
• W3024321941 citedByCount "3" @default.
• W3024321941 countsByYear W30243219412022 @default.
• W3024321941 countsByYear W30243219412023 @default.
• W3024321941 crossrefType "journal-article" @default.
• W3024321941 hasAuthorship W3024321941A5004102451 @default.
• W3024321941 hasAuthorship W3024321941A5031776620 @default.
• W3024321941 hasAuthorship W3024321941A5061668278 @default.
• W3024321941 hasAuthorship W3024321941A5088403251 @default.
• W3024321941 hasConcept C104317684 @default.
• W3024321941 hasConcept C126322002 @default.
• W3024321941 hasConcept C134018914 @default.
• W3024321941 hasConcept C15744967 @default.
• W3024321941 hasConcept C169760540 @default.
• W3024321941 hasConcept C170493617 @default.
• W3024321941 hasConcept C2775864247 @default.
• W3024321941 hasConcept C3020172569 @default.
• W3024321941 hasConcept C42407357 @default.
• W3024321941 hasConcept C501734568 @default.
• W3024321941 hasConcept C513476851 @default.
• W3024321941 hasConcept C53927964 @default.
• W3024321941 hasConcept C54355233 @default.
• W3024321941 hasConcept C67636389 @default.
• W3024321941 hasConcept C71924100 @default.
• W3024321941 hasConcept C72563966 @default.
• W3024321941 hasConcept C86803240 @default.
• W3024321941 hasConceptScore W3024321941C104317684 @default.
• W3024321941 hasConceptScore W3024321941C126322002 @default.
• W3024321941 hasConceptScore W3024321941C134018914 @default.
• W3024321941 hasConceptScore W3024321941C15744967 @default.
• W3024321941 hasConceptScore W3024321941C169760540 @default.
• W3024321941 hasConceptScore W3024321941C170493617 @default.
• W3024321941 hasConceptScore W3024321941C2775864247 @default.
• W3024321941 hasConceptScore W3024321941C3020172569 @default.
• W3024321941 hasConceptScore W3024321941C42407357 @default.
• W3024321941 hasConceptScore W3024321941C501734568 @default.
• W3024321941 hasConceptScore W3024321941C513476851 @default.
• W3024321941 hasConceptScore W3024321941C53927964 @default.
• W3024321941 hasConceptScore W3024321941C54355233 @default.
• W3024321941 hasConceptScore W3024321941C67636389 @default.
• W3024321941 hasConceptScore W3024321941C71924100 @default.
• W3024321941 hasConceptScore W3024321941C72563966 @default.
• W3024321941 hasConceptScore W3024321941C86803240 @default.
• W3024321941 hasIssue "2" @default.
• W3024321941 hasLocation W30243219411 @default.
• W3024321941 hasOpenAccess W3024321941 @default.
• W3024321941 hasPrimaryLocation W30243219411 @default.
• W3024321941 hasRelatedWork W1985798149 @default.
• W3024321941 hasRelatedWork W1994492867 @default.
• W3024321941 hasRelatedWork W2002128513 @default.

• next