FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024355576> ?p ?o ?g. }

• W3024355576 endingPage "275" @default.
• W3024355576 startingPage "269" @default.
• W3024355576 abstract "Background Patients with primary aldosteronism (PA) without apparent adrenal nodularity have not been well characterised in the literature. The aim of this study was to assess for unilateral aldosterone hypersecretion among patients with primary aldosteronism with normal-appearing adrenals using adrenal vein sampling (AVS). Methods In this cross-sectional study performed at a Canadian tertiary care centre, we reviewed all consecutive PA patients lacking a definitive adrenal nodule who were referred for AVS in the work-up of PA between January 2006 and May 2018. AVS indications included an elevated aldosterone-to-renin ratio and high-probability features of PA. Results In total, 174 patients were included (mean age, 52.0 years; 62.6% male), and 70 (40.2%) had unilateral aldosterone hypersecretion. There was a positive linear association between higher age categories (by decade) and lateralisation (P = 0.03). For every decade of age, there was a 30% higher odds of lateralisation (odds ratio, 1.03 per year; 95% confidence interval, 1.00-1.05). The frequency of lateralisation was higher in males compared with females (47.7% vs 27.7%), with a 2-fold greater odds of unilateral disease (odds ratio, 2.38; 95% confidence interval, 1.23-4.61). Traditional biomarkers of lateralisation among patients with adrenal nodules (eg, serum potassium and aldosterone-to-renin ratio levels) were not predictive of lateralisation in this population. Conclusions Many patients with PA who lack definitive adrenal nodules have lateralising disease. Efforts to optimise referrals for AVS may be prioritised by focusing on patients most likely to have unilateral disease, especially males and older adults." @default.
• W3024355576 created "2020-05-21" @default.
• W3024355576 creator A5023934848 @default.
• W3024355576 creator A5024668327 @default.
• W3024355576 creator A5053917367 @default.
• W3024355576 creator A5055716445 @default.
• W3024355576 creator A5084251116 @default.
• W3024355576 date "2021-02-01" @default.
• W3024355576 modified "2023-09-27" @default.
• W3024355576 title "Unilateral Disease Is Common in Patients With Primary Aldosteronism Without Adrenal Nodules" @default.
• W3024355576 cites W1516848070 @default.
• W3024355576 cites W1980850309 @default.
• W3024355576 cites W1995096457 @default.
• W3024355576 cites W2004150662 @default.
• W3024355576 cites W2013467613 @default.
• W3024355576 cites W2026840530 @default.
• W3024355576 cites W2031092755 @default.
• W3024355576 cites W2031675450 @default.
• W3024355576 cites W2045516356 @default.
• W3024355576 cites W2049262968 @default.
• W3024355576 cites W2061341378 @default.
• W3024355576 cites W2061429541 @default.
• W3024355576 cites W2063141912 @default.
• W3024355576 cites W2087855842 @default.
• W3024355576 cites W2095527951 @default.
• W3024355576 cites W2106586562 @default.
• W3024355576 cites W2124736012 @default.
• W3024355576 cites W2129925362 @default.
• W3024355576 cites W2148671035 @default.
• W3024355576 cites W2152669614 @default.
• W3024355576 cites W2166561686 @default.
• W3024355576 cites W2180775593 @default.
• W3024355576 cites W2285739131 @default.
• W3024355576 cites W2290633895 @default.
• W3024355576 cites W2318109202 @default.
• W3024355576 cites W2387913746 @default.
• W3024355576 cites W2426108768 @default.
• W3024355576 cites W2513397587 @default.
• W3024355576 cites W2515022149 @default.
• W3024355576 cites W2568914182 @default.
• W3024355576 cites W2595206132 @default.
• W3024355576 cites W2606655992 @default.
• W3024355576 cites W2617388174 @default.
• W3024355576 cites W2623629155 @default.
• W3024355576 cites W2754576630 @default.
• W3024355576 cites W2765314468 @default.
• W3024355576 cites W2766470307 @default.
• W3024355576 cites W2789097506 @default.
• W3024355576 cites W2793611804 @default.
• W3024355576 cites W2802470363 @default.
• W3024355576 cites W2864747507 @default.
• W3024355576 cites W2895985163 @default.
• W3024355576 cites W2900441616 @default.
• W3024355576 cites W2906537505 @default.
• W3024355576 cites W2914915730 @default.
• W3024355576 cites W2917125411 @default.
• W3024355576 cites W2921867168 @default.
• W3024355576 cites W2991477906 @default.
• W3024355576 cites W4252016380 @default.
• W3024355576 cites W4368240604 @default.
• W3024355576 doi "https://doi.org/10.1016/j.cjca.2020.05.013" @default.
• W3024355576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32428615" @default.
• W3024355576 hasPublicationYear "2021" @default.
• W3024355576 type Work @default.
• W3024355576 sameAs 3024355576 @default.
• W3024355576 citedByCount "5" @default.
• W3024355576 countsByYear W30243555762021 @default.
• W3024355576 countsByYear W30243555762022 @default.
• W3024355576 crossrefType "journal-article" @default.
• W3024355576 hasAuthorship W3024355576A5023934848 @default.
• W3024355576 hasAuthorship W3024355576A5024668327 @default.
• W3024355576 hasAuthorship W3024355576A5053917367 @default.
• W3024355576 hasAuthorship W3024355576A5055716445 @default.
• W3024355576 hasAuthorship W3024355576A5084251116 @default.
• W3024355576 hasConcept C126322002 @default.
• W3024355576 hasConcept C126894567 @default.
• W3024355576 hasConcept C156957248 @default.
• W3024355576 hasConcept C2776292634 @default.
• W3024355576 hasConcept C2778525890 @default.
• W3024355576 hasConcept C2780233176 @default.
• W3024355576 hasConcept C44249647 @default.
• W3024355576 hasConcept C71924100 @default.
• W3024355576 hasConcept C90924648 @default.
• W3024355576 hasConceptScore W3024355576C126322002 @default.
• W3024355576 hasConceptScore W3024355576C126894567 @default.
• W3024355576 hasConceptScore W3024355576C156957248 @default.
• W3024355576 hasConceptScore W3024355576C2776292634 @default.
• W3024355576 hasConceptScore W3024355576C2778525890 @default.
• W3024355576 hasConceptScore W3024355576C2780233176 @default.
• W3024355576 hasConceptScore W3024355576C44249647 @default.
• W3024355576 hasConceptScore W3024355576C71924100 @default.
• W3024355576 hasConceptScore W3024355576C90924648 @default.
• W3024355576 hasFunder F4320327924 @default.
• W3024355576 hasIssue "2" @default.
• W3024355576 hasLocation W30243555761 @default.
• W3024355576 hasOpenAccess W3024355576 @default.
• W3024355576 hasPrimaryLocation W30243555761 @default.
• W3024355576 hasRelatedWork W1970251377 @default.

• next