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- W3024470121 abstract "Researchers have extensively used nanofibrous scaffolds as drug delivery systems for transdermal and topical applications. This method employs improved drug loading in the nanofibers to maintain a slow and sustained release of the drug for an advanced tissue regeneration process. Electrospun nanofibrous scaffolds offer many desirable advantages as drug delivery systems. Researchers have developed an artificial skin equivalent containing permeability and lipid profiles similar to cadaver skin or animal skin to evaluate the drug permeation rate in vitro. Nanofiber-based drug delivery systems increase the drug concentration significantly in the delivery vesicle and consequently intensify the drug flux. The drug release kinetics can be modulated to meet the specific clinical needs by changing various parameters, such as the fiber morphology, the drug-to-polymer ratio, and the porosity of the scaffold. An in vivo study on a rat model showed promising healing of an infected wound on treatment with a drug-loaded electrospun fibrous mat." @default.
- W3024470121 created "2020-05-21" @default.
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- W3024470121 date "2020-05-13" @default.
- W3024470121 modified "2023-09-25" @default.
- W3024470121 title "Recent Developments in Transdermal Drug Delivery Systems Based on an Electrospun Nanofibrous Scaffold" @default.
- W3024470121 cites W2147038478 @default.
- W3024470121 doi "https://doi.org/10.1201/9781003055815-13" @default.
- W3024470121 hasPublicationYear "2020" @default.
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