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- W3024551421 abstract "Objective: To evaluate the relationships between anatomical changes and treatment outcomes after modified velopharyngeal surgery in obstructive sleep apnea hypopnea syndrome (OSAHS) patients with the soft palate drooping. Methods: From November 2011 to November 2015, 44 OSHS patients (AHI 5-30 times/h) with the soft palate drooping determined by Muller test and drug-induced sleep endoscopy (DISE) were randomly selected. Treatment group included 23 patients who underwent modified velopharyngeal surgery, in which uvula was preserved and soft palate was shortened and advanced. Control group included 21 patients who received conventional UPPP surgery.Compared the differences in preoperative and postoperative Epworth Sleepiness Scale (ESS), Numeric Rating Scale (NRS), lowest arterial blood oxygen saturation (LSaO(2)), and apnea hypoventilation index (AHI) between the two groups. Each data rows normality test. The two groups' preoperative and postoperative data row intra-group comparison and matching t test. Used the independent sample t test after homogeneity of variance test to compare the two groups. The difference was statistically significant when P<0.05. Results: There were statistically significant differences in AHI , LSaO(2) and ESS score between before and after surgery in individual groups. There were not significant differences in preoperative AHI and LSaO(2) between the two groups, but with a higher ESS in treatment group compared to control group. There were no statistically significant differences in postoperative AHI, LSaO(2) or ESS between the two groups. Compared with control group, treatment group had a lower postoperative pain scale score (4.3±1.3 vs 6.3±0.8, P=0.000) and a shorter time to resume normal eating ((6.7±1.6) d vs (15.5±3.5) d, P=0.000). Conclusion: OSAHS patients (AHI 5-30 times/h) with the soft palate drooping are more likely to have favorable anatomical changes after revised velopharyngeal surgery.目的: 探讨软腭折叠术在阻塞性睡眠呼吸暂停低通气综合征(OSAHS)软腭低垂帷幔型患者中的治疗效果。 方法: 回顾性分析2011年11月至2015年11月首都医科大学附属北京友谊医院耳鼻咽喉头颈外科收治的44例OSAHS患者的病历资料,患者均经多道睡眠监测(PSG)确诊为轻/中度阻塞,药物诱导脑电双频指数监测睡眠状态纤维喉镜下上气道阻塞平面定位确诊为单纯软腭平面狭窄。其中治疗组23例,行软腭折叠术:软腭部行月牙形切口,去除腭帆间隙脂肪组织,并将软腭肌层折叠缝合,缩短软腭长度,增加软腭张力,软腭游离缘光滑前倾,软腭后间隙增宽。若伴有扁桃体肥大,侧索肥厚再增加咽侧壁成形术。对照组21例,行悬雍垂腭咽成形术。根据Epworth嗜睡量表(ESS)评分嗜睡程度,对局部疼痛按数字评定量表(Numeric Rating Scale, NRS)进行量化比较,比较两组术前及术后6个月呼吸暂停低通气指数(AHI)、最低动脉血氧饱和度(LSaO(2))及ESS评分。各组数据行正态分析,两组手术前后数据组内比较行配对t检验;组间比较先行方差齐性的Levene检验,再采用独立样本t检验,P<0.05为差异有统计学意义。 结果: 治疗组、对照组分别行组内比较,术前及术后6个月AHI、LSaO(2)、ESS评分差异均有统计学意义。术前两组间AHI、LSaO(2)比较差异均无统计学意义,治疗组ESS评分高于对照组,差异有统计学意义;术后6个月两组间AHI、LSaO(2)、ESS评分差异均无统计学意义,治疗组较对照组的NRS评分低(4.3±1.3比6.3±0.8),恢复正常进食时间短[(6.7±1.6)d比(15.5±3.5)d],差异均有统计学意义(P值均=0.000)。 结论: 软腭低垂帷幔型的OSAHS患者行软腭折叠术,微创且有效,术后恢复快,无后遗症。." @default.
- W3024551421 created "2020-05-21" @default.
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- W3024551421 date "2017-02-07" @default.
- W3024551421 modified "2023-10-18" @default.
- W3024551421 title "[Therapeutic effectiveness of the soft palate fold surgery in patients with obstructive sleep apnea hypopnea syndrome]." @default.
- W3024551421 doi "https://doi.org/10.3760/cma.j.issn.1673-0860.2017.02.005" @default.
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