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- W3024687041 abstract "Objective: To assess the retinal image quality of the normal northern rural Chinese adult population. Methods: A normal population-based, cross-sectional study. From Oct, 2012 to Jan 2013, a clustered, random sampling procedure was used to select normal population who visual acuity≤ 0(LogMAR) and 30-69 years old from 2 villages. All eligible subjects were invited to undergo a comprehensive eye examination, and the retinal image quality related index were examined with pupil 4 mm using objective optical quality analysis systemⅡ(OQAS Ⅱ, Visiometrics, Spain), including MTFcutoff, VA20, VA9, PSF50, PSF10, OSI, SR. And describe the retinal image quality of different age group, including 30-39y, 40-49y, 50-59y, 60-69y. Results: Among 1 108 participants (61.9%) that completed examinations in our center, 681 participants (1 362 eyes) were recruited. There were 146, 586, 440 and 190 eyes in each group. The spherical equivalent refraction of each group was (-0.35±0.84), (-0.19±0.50), (-0.03±0.54) and (0.20±0.71) D. The best corrected vision acuity of each group was -0.02±0.04, -0.01±0.03, -0.01±0.02 and -0.00±0.01. The MTFcutoff of each group was (37.06±9.31), (36.69±8.93), (36.52±9.05) and (32.61±10.08) c/deg. Retinal imaging parameters were significantly different(MTFcutoff: MD=4.45, SR:MD=0.03, PSF50: MD=-0.45, PSF10: MD=-2.87, VA20:MD=0.13, A9:MD=0.09, OSI:MD=-0.41, P<0.001)between aged 30-39 group and aged 60-69 group. Objective scattering index (OSI) were significantly different(MD=-0.13, P=0.004)between aged 30-39 group and aged 50-59 group. Retinal imaging parameters were significantly different(MTFcutoff:MD=4.45, SR:MD=0.03, PSF50:MD=-0.45, PSF10:MD=-2.87, VA20:MD=0.13, VA9: MD=0.09, OSI: MD=-0.41, P<0.001)between aged 40-49 group and aged 60-69 group. Retinal imageing parameters were significantly different(MTFcutoff: MD=4.45, SR: MD=0.03, PSF50: MD=-0.45, PSF10: MD=-2.87, VA20:MD=0.13, VA9:MD=0.09, OSI:MD=-0.41,P<0.001)between aged 50-59 group and aged 60-69 group. Conclusion: Retinal image quality was gradually worse over time in the northern rural Chinese adult population. (Chin J Ophthalmol, 2018, 54:593-598).目的： 了解我国北方农村地区自然人群中成人眼视网膜成像质量分布特征。 方法： 横断面研究。将邯郸眼病研究中经随机整群抽样的永年县13个行政村的两个行政村的30~69岁排除眼部病变后视力≤ 0（LogMAR）的健康受试者纳入研究。所有受试者在邯郸眼病研究Ⅱ的中央检查中心进行眼科和全身检查。收集受试者等效球镜度数和最佳矫正视力（BCVA）数据，并采用OQASⅡ客观视觉质量双通道分析系统测量4 mm瞳孔直径下视网膜成像质量参数，包括调制传递函数截止频率（MTFcutoff）、20%对比度视力（VA20）、9%对比度视力（VA9），50%和10%峰值点扩散函数宽度（PSF50、PSF10）、斯特列尔比值（SR）、客观散射指数（OSI）。比较30~39岁、40~49岁、50~59岁、60~69岁受试者视网膜成像质量各参数之间差别。计量资料的组间比较采用方差分析，两两比较采用LSD检验，检验水准校正为0.008。 结果： 1 108人（61.9%）经核实后前来中心检查点完成相关检查的受试者中，符合入选排除标准共计681人（1 362只眼），其中男性328人（656只眼），女性353人（706只眼）；年龄（50.1±8.8）岁。30~39岁、40~49岁、50~59岁、60~69岁4个年龄段受试者等效球镜度数分别为（-0.35±0.84）、（-0.19±0.50）、（-0.03±0.54）和（0.20±0.71）D，各年龄段受试者最佳矫正视力分别为-0.02±0.04、-0.01±0.03、-0.01±0.02和-0.00±0.01，各年龄段受试者MTFcutoff分别为（37.06±9.31）、（36.69±8.93）、（36.52±9.05）和（32.61±10.08）周/度。其中30~39岁与60~69岁比较，MTFcutoff（MD=4.45，P<0.001）、SR（MD=0.03，P<0.001）、PSF50（MD=-0.45，P<0.001）、PSF10（MD=-2.87，P<0.001）、VA20（MD=0.13，P<0.001）、VA9（MD=0.09，P<0.001）、OSI（MD=-0.41，P<0.001），差异均有统计学意义，与50~59岁比较，OSI差异有统计学意义（MD=-0.13，P=0.004），与40~49岁比较，差异均无统计学意义（P>0.05）；40~49岁与60~69岁比较，MTFcutoff（MD=4.07，P<0.001）、SR（MD=0.02，P<0.001）、PSF50（MD=-0.46，P<0.001）、PSF10（MD=-2.67，P<0.001）、VA20（MD=0.11，P<0.001）、VA9（MD=0.07，P<0.001）、OSI（MD=-0.34，P<0.001），差异均有统计学意义；与50~59岁比较，差异均无统计学意义（P>0.05）；50~59岁与60~69岁相比，MTFcutoff（MD=3.91，P<0.001）、SR（MD=0.02，P<0.001）、PSF50（MD=-0.42，P<0.001）、PSF10（MD=-1.99，P<0.001）、VA20（MD=0.10，P<0.001）、VA9（MD=0.06，P<0.001）、OSI（MD=-0.28，P<0.001），差异均有统计学意义。 结论： 我国北方农村地区30岁以上成年人群中，视网膜成像质量随年龄增长而逐渐下降，60岁后明显下降，即使视力正常且裂隙灯检查未见晶状体混浊的人眼，同样存在视网膜成像质量下降及眼内散射升高的可能。（中华眼科杂志，2018，54：593-598）." @default.
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- W3024687041 date "2018-08-11" @default.
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- W3024687041 title "[Retinal image quality in northern rural Chinese adult population]." @default.
- W3024687041 doi "https://doi.org/10.3760/cma.j.issn.0412-4081.2018.08.006" @default.
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