Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024711761> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W3024711761 endingPage "1291" @default.
- W3024711761 startingPage "1285" @default.
- W3024711761 abstract "Synthesis of new antioxidants and enzyme inhibitors is an active area of research in pharmaceutical sciences. This can be used for development of new active product ingredients which can prevent body from different diseases. This study comprises of preparation of transition metal complexes using 4-(4-bromophenyl)-2,2'-bipyridine (BPBP) and their screening for antioxidant and lipoxygenase inhibition properties. 4-(4-bromophenyl)-[2,2'-bipyridine]-6-carboxylic acid was used as starting material and its decarboxylation resulted in BPBP. Decarboxylation by conventional heating method was compared with microwave decarboxylation method. Selected metal complexes of the ligand were synthesized with Ruthenium (II), Iron (II) and Cobalt (II) ions. The complexes were characterized using UV, IR, 1H-NMR, ESI-MS and CHNS techniques. It was observed that BPBP acted as a bidentate ligand. The metal to ligand stoichiometry was 1:3 for all the synthesized complexes. The complexes had octahedral structure with C3 symmetry. The antioxidant activity was evaluated using free radical scavenging assay. BPBP showed insignificant antioxidant and lipoxygenase activities while its transition metal complexes showed promising activities. Antioxidant activity of Fe and Co-complexes was found significantly higher than the reference drug used in this study." @default.
- W3024711761 created "2020-05-21" @default.
- W3024711761 creator A5010640321 @default.
- W3024711761 creator A5021714719 @default.
- W3024711761 creator A5072396411 @default.
- W3024711761 date "2019-05-01" @default.
- W3024711761 modified "2023-09-26" @default.
- W3024711761 title "Antioxidant and lipoxygenase inhibition studies of 4-(4-bromophenyl)-2,2'-bipyridine and its metal complexes Synthesis, characterization and biological screening." @default.
- W3024711761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/31551205" @default.
- W3024711761 hasPublicationYear "2019" @default.
- W3024711761 type Work @default.
- W3024711761 sameAs 3024711761 @default.
- W3024711761 citedByCount "0" @default.
- W3024711761 crossrefType "journal-article" @default.
- W3024711761 hasAuthorship W3024711761A5010640321 @default.
- W3024711761 hasAuthorship W3024711761A5021714719 @default.
- W3024711761 hasAuthorship W3024711761A5072396411 @default.
- W3024711761 hasConcept C115624301 @default.
- W3024711761 hasConcept C116569031 @default.
- W3024711761 hasConcept C155647269 @default.
- W3024711761 hasConcept C161790260 @default.
- W3024711761 hasConcept C170493617 @default.
- W3024711761 hasConcept C178516000 @default.
- W3024711761 hasConcept C178790620 @default.
- W3024711761 hasConcept C181199279 @default.
- W3024711761 hasConcept C185592680 @default.
- W3024711761 hasConcept C199164860 @default.
- W3024711761 hasConcept C2778004101 @default.
- W3024711761 hasConcept C2779336533 @default.
- W3024711761 hasConcept C2780595602 @default.
- W3024711761 hasConcept C2780857362 @default.
- W3024711761 hasConcept C2781031786 @default.
- W3024711761 hasConcept C2781401929 @default.
- W3024711761 hasConcept C39297587 @default.
- W3024711761 hasConcept C544153396 @default.
- W3024711761 hasConcept C55493867 @default.
- W3024711761 hasConcept C555196967 @default.
- W3024711761 hasConcept C71240020 @default.
- W3024711761 hasConceptScore W3024711761C115624301 @default.
- W3024711761 hasConceptScore W3024711761C116569031 @default.
- W3024711761 hasConceptScore W3024711761C155647269 @default.
- W3024711761 hasConceptScore W3024711761C161790260 @default.
- W3024711761 hasConceptScore W3024711761C170493617 @default.
- W3024711761 hasConceptScore W3024711761C178516000 @default.
- W3024711761 hasConceptScore W3024711761C178790620 @default.
- W3024711761 hasConceptScore W3024711761C181199279 @default.
- W3024711761 hasConceptScore W3024711761C185592680 @default.
- W3024711761 hasConceptScore W3024711761C199164860 @default.
- W3024711761 hasConceptScore W3024711761C2778004101 @default.
- W3024711761 hasConceptScore W3024711761C2779336533 @default.
- W3024711761 hasConceptScore W3024711761C2780595602 @default.
- W3024711761 hasConceptScore W3024711761C2780857362 @default.
- W3024711761 hasConceptScore W3024711761C2781031786 @default.
- W3024711761 hasConceptScore W3024711761C2781401929 @default.
- W3024711761 hasConceptScore W3024711761C39297587 @default.
- W3024711761 hasConceptScore W3024711761C544153396 @default.
- W3024711761 hasConceptScore W3024711761C55493867 @default.
- W3024711761 hasConceptScore W3024711761C555196967 @default.
- W3024711761 hasConceptScore W3024711761C71240020 @default.
- W3024711761 hasIssue "3 Special" @default.
- W3024711761 hasLocation W30247117611 @default.
- W3024711761 hasOpenAccess W3024711761 @default.
- W3024711761 hasPrimaryLocation W30247117611 @default.
- W3024711761 hasRelatedWork W1868841180 @default.
- W3024711761 hasRelatedWork W1882251448 @default.
- W3024711761 hasRelatedWork W2012698699 @default.
- W3024711761 hasRelatedWork W2017456826 @default.
- W3024711761 hasRelatedWork W2046384451 @default.
- W3024711761 hasRelatedWork W2049061599 @default.
- W3024711761 hasRelatedWork W2076863134 @default.
- W3024711761 hasRelatedWork W2096306259 @default.
- W3024711761 hasRelatedWork W2120425736 @default.
- W3024711761 hasRelatedWork W3024711761 @default.
- W3024711761 hasVolume "32" @default.
- W3024711761 isParatext "false" @default.
- W3024711761 isRetracted "false" @default.
- W3024711761 magId "3024711761" @default.
- W3024711761 workType "article" @default.