Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024726737> ?p ?o ?g. }
- W3024726737 abstract "Eukaryotic cells in living tissues form dynamic patterns with spatially varying orientational order that affects important physiological processes such as apoptosis and cell migration. The challenge is how to impart a predesigned map of orientational order onto a growing tissue. Here, we demonstrate an approach to produce cell monolayers of human dermal fibroblasts with predesigned orientational patterns and topological defects using a photoaligned liquid crystal elastomer (LCE) that swells anisotropically in an aqueous medium. The patterns inscribed into the LCE are replicated by the tissue monolayer and cause a strong spatial variation of cells phenotype, their surface density, and number density fluctuations. Unbinding dynamics of defect pairs intrinsic to active matter is suppressed by anisotropic surface anchoring allowing the estimation of the elastic characteristics of the tissues. The demonstrated patterned LCE approach has potential to control the collective behavior of cells in living tissues, cell differentiation, and tissue morphogenesis." @default.
- W3024726737 created "2020-05-21" @default.
- W3024726737 creator A5004644751 @default.
- W3024726737 creator A5005014132 @default.
- W3024726737 creator A5017469181 @default.
- W3024726737 creator A5025050356 @default.
- W3024726737 creator A5031341894 @default.
- W3024726737 creator A5043516484 @default.
- W3024726737 creator A5043580930 @default.
- W3024726737 creator A5070573424 @default.
- W3024726737 date "2020-05-15" @default.
- W3024726737 modified "2023-10-15" @default.
- W3024726737 title "Topology control of human fibroblast cells monolayer by liquid crystal elastomer" @default.
- W3024726737 cites W1518694232 @default.
- W3024726737 cites W1971030181 @default.
- W3024726737 cites W1972887127 @default.
- W3024726737 cites W1992084946 @default.
- W3024726737 cites W1996108341 @default.
- W3024726737 cites W1997974665 @default.
- W3024726737 cites W2004098988 @default.
- W3024726737 cites W2013539049 @default.
- W3024726737 cites W2016250229 @default.
- W3024726737 cites W2024250498 @default.
- W3024726737 cites W2055276703 @default.
- W3024726737 cites W2059667163 @default.
- W3024726737 cites W2074574519 @default.
- W3024726737 cites W2091445641 @default.
- W3024726737 cites W2094971551 @default.
- W3024726737 cites W2127722806 @default.
- W3024726737 cites W2130303535 @default.
- W3024726737 cites W2134256482 @default.
- W3024726737 cites W2138977668 @default.
- W3024726737 cites W2139378301 @default.
- W3024726737 cites W2167279371 @default.
- W3024726737 cites W2168147240 @default.
- W3024726737 cites W2290427974 @default.
- W3024726737 cites W2336881770 @default.
- W3024726737 cites W2512365985 @default.
- W3024726737 cites W2517102863 @default.
- W3024726737 cites W2520869106 @default.
- W3024726737 cites W2550715989 @default.
- W3024726737 cites W2598793818 @default.
- W3024726737 cites W2606063864 @default.
- W3024726737 cites W2606454966 @default.
- W3024726737 cites W2611167584 @default.
- W3024726737 cites W2775257534 @default.
- W3024726737 cites W2795790438 @default.
- W3024726737 cites W2798033522 @default.
- W3024726737 cites W2889062661 @default.
- W3024726737 cites W2907618680 @default.
- W3024726737 cites W2952802990 @default.
- W3024726737 doi "https://doi.org/10.1126/sciadv.aaz6485" @default.
- W3024726737 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7220327" @default.
- W3024726737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32426499" @default.
- W3024726737 hasPublicationYear "2020" @default.
- W3024726737 type Work @default.
- W3024726737 sameAs 3024726737 @default.
- W3024726737 citedByCount "82" @default.
- W3024726737 countsByYear W30247267372020 @default.
- W3024726737 countsByYear W30247267372021 @default.
- W3024726737 countsByYear W30247267372022 @default.
- W3024726737 countsByYear W30247267372023 @default.
- W3024726737 crossrefType "journal-article" @default.
- W3024726737 hasAuthorship W3024726737A5004644751 @default.
- W3024726737 hasAuthorship W3024726737A5005014132 @default.
- W3024726737 hasAuthorship W3024726737A5017469181 @default.
- W3024726737 hasAuthorship W3024726737A5025050356 @default.
- W3024726737 hasAuthorship W3024726737A5031341894 @default.
- W3024726737 hasAuthorship W3024726737A5043516484 @default.
- W3024726737 hasAuthorship W3024726737A5043580930 @default.
- W3024726737 hasAuthorship W3024726737A5070573424 @default.
- W3024726737 hasBestOaLocation W30247267371 @default.
- W3024726737 hasConcept C104317684 @default.
- W3024726737 hasConcept C104862878 @default.
- W3024726737 hasConcept C121332964 @default.
- W3024726737 hasConcept C12554922 @default.
- W3024726737 hasConcept C13274807 @default.
- W3024726737 hasConcept C159467904 @default.
- W3024726737 hasConcept C159985019 @default.
- W3024726737 hasConcept C171250308 @default.
- W3024726737 hasConcept C185592680 @default.
- W3024726737 hasConcept C192562407 @default.
- W3024726737 hasConcept C26873012 @default.
- W3024726737 hasConcept C2777803738 @default.
- W3024726737 hasConcept C2780381497 @default.
- W3024726737 hasConcept C38052585 @default.
- W3024726737 hasConcept C40692019 @default.
- W3024726737 hasConcept C49040817 @default.
- W3024726737 hasConcept C49892992 @default.
- W3024726737 hasConcept C54355233 @default.
- W3024726737 hasConcept C55493867 @default.
- W3024726737 hasConcept C7070889 @default.
- W3024726737 hasConcept C81885089 @default.
- W3024726737 hasConcept C86803240 @default.
- W3024726737 hasConcept C95444343 @default.
- W3024726737 hasConceptScore W3024726737C104317684 @default.
- W3024726737 hasConceptScore W3024726737C104862878 @default.
- W3024726737 hasConceptScore W3024726737C121332964 @default.
- W3024726737 hasConceptScore W3024726737C12554922 @default.
- W3024726737 hasConceptScore W3024726737C13274807 @default.