FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3024760839> ?p ?o ?g. }

• W3024760839 abstract "microRNAs regulate subcellular functions through distinct molecular mechanisms. In this study, we used normal and pathogenic fibroblasts in pelvic fracture urethral distraction defects (PFUDD) patients. PFUDD is a common disease that could severely affect patients' life quality, yet little is known about the molecular mechanism associated with pathogenic fibrosis in PFUDD. Our data showed that let-7i-5p performs a multi-functional role in distinct signaling transduction pathways involved in cell morphology and cell migration in both normal and pathogenic fibroblasts. By analyzing the molecular mechanism associated with its functions, we found that let-7i-5p regulates through its direct target genes involved in collagen metabolism, cell proliferation and differentiation, TGF-beta signaling, DNA repair and ubiquitination, gene silencing and oxygen homeostasis. We conclude that let-7i-5p plays an essential role in regulating cell shape and tissue elasticity, cell migration, cell morphology and cytoskeleton, and could serve as a potential target for clinical treatment of urethral stricture patients." @default.
• W3024760839 created "2020-05-21" @default.
• W3024760839 creator A5015096273 @default.
• W3024760839 creator A5018863416 @default.
• W3024760839 creator A5025437829 @default.
• W3024760839 creator A5042219170 @default.
• W3024760839 creator A5046236881 @default.
• W3024760839 creator A5061930836 @default.
• W3024760839 creator A5063466392 @default.
• W3024760839 creator A5082857859 @default.
• W3024760839 creator A5086177844 @default.
• W3024760839 date "2020-05-14" @default.
• W3024760839 modified "2023-10-16" @default.
• W3024760839 title "Let-7i-5p Regulation of Cell Morphology and Migration Through Distinct Signaling Pathways in Normal and Pathogenic Urethral Fibroblasts" @default.
• W3024760839 cites W1489063373 @default.
• W3024760839 cites W1920303762 @default.
• W3024760839 cites W1975524132 @default.
• W3024760839 cites W2021328201 @default.
• W3024760839 cites W2027859720 @default.
• W3024760839 cites W2034110625 @default.
• W3024760839 cites W2067440962 @default.
• W3024760839 cites W2098662346 @default.
• W3024760839 cites W2107277218 @default.
• W3024760839 cites W2113546559 @default.
• W3024760839 cites W2115223685 @default.
• W3024760839 cites W2142174182 @default.
• W3024760839 cites W2166196657 @default.
• W3024760839 cites W2170650062 @default.
• W3024760839 cites W2192080449 @default.
• W3024760839 cites W2192919605 @default.
• W3024760839 cites W2233523867 @default.
• W3024760839 cites W2288482887 @default.
• W3024760839 cites W2328453756 @default.
• W3024760839 cites W2335793642 @default.
• W3024760839 cites W2418525296 @default.
• W3024760839 cites W2486665380 @default.
• W3024760839 cites W2569800935 @default.
• W3024760839 cites W2614928875 @default.
• W3024760839 cites W2728826798 @default.
• W3024760839 cites W2766833437 @default.
• W3024760839 cites W2767019448 @default.
• W3024760839 cites W2786040837 @default.
• W3024760839 cites W2786619340 @default.
• W3024760839 cites W2791011850 @default.
• W3024760839 doi "https://doi.org/10.3389/fbioe.2020.00428" @default.
• W3024760839 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7240038" @default.
• W3024760839 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32478052" @default.
• W3024760839 hasPublicationYear "2020" @default.
• W3024760839 type Work @default.
• W3024760839 sameAs 3024760839 @default.
• W3024760839 citedByCount "4" @default.
• W3024760839 countsByYear W30247608392021 @default.
• W3024760839 countsByYear W30247608392022 @default.
• W3024760839 crossrefType "journal-article" @default.
• W3024760839 hasAuthorship W3024760839A5015096273 @default.
• W3024760839 hasAuthorship W3024760839A5018863416 @default.
• W3024760839 hasAuthorship W3024760839A5025437829 @default.
• W3024760839 hasAuthorship W3024760839A5042219170 @default.
• W3024760839 hasAuthorship W3024760839A5046236881 @default.
• W3024760839 hasAuthorship W3024760839A5061930836 @default.
• W3024760839 hasAuthorship W3024760839A5063466392 @default.
• W3024760839 hasAuthorship W3024760839A5082857859 @default.
• W3024760839 hasAuthorship W3024760839A5086177844 @default.
• W3024760839 hasBestOaLocation W30247608391 @default.
• W3024760839 hasConcept C104317684 @default.
• W3024760839 hasConcept C119056186 @default.
• W3024760839 hasConcept C137738243 @default.
• W3024760839 hasConcept C1491633281 @default.
• W3024760839 hasConcept C150555746 @default.
• W3024760839 hasConcept C54355233 @default.
• W3024760839 hasConcept C62112901 @default.
• W3024760839 hasConcept C62478195 @default.
• W3024760839 hasConcept C86803240 @default.
• W3024760839 hasConcept C95444343 @default.
• W3024760839 hasConceptScore W3024760839C104317684 @default.
• W3024760839 hasConceptScore W3024760839C119056186 @default.
• W3024760839 hasConceptScore W3024760839C137738243 @default.
• W3024760839 hasConceptScore W3024760839C1491633281 @default.
• W3024760839 hasConceptScore W3024760839C150555746 @default.
• W3024760839 hasConceptScore W3024760839C54355233 @default.
• W3024760839 hasConceptScore W3024760839C62112901 @default.
• W3024760839 hasConceptScore W3024760839C62478195 @default.
• W3024760839 hasConceptScore W3024760839C86803240 @default.
• W3024760839 hasConceptScore W3024760839C95444343 @default.
• W3024760839 hasLocation W30247608391 @default.
• W3024760839 hasLocation W30247608392 @default.
• W3024760839 hasLocation W30247608393 @default.
• W3024760839 hasLocation W30247608394 @default.
• W3024760839 hasOpenAccess W3024760839 @default.
• W3024760839 hasPrimaryLocation W30247608391 @default.
• W3024760839 hasRelatedWork W1176469767 @default.
• W3024760839 hasRelatedWork W1983658560 @default.
• W3024760839 hasRelatedWork W1990723931 @default.
• W3024760839 hasRelatedWork W2072529897 @default.
• W3024760839 hasRelatedWork W2083693850 @default.
• W3024760839 hasRelatedWork W2107107815 @default.
• W3024760839 hasRelatedWork W2161171309 @default.
• W3024760839 hasRelatedWork W3092010054 @default.
• W3024760839 hasRelatedWork W3125309376 @default.
• W3024760839 hasRelatedWork W3183075330 @default.

• next