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- W3025101016 abstract "To analyze the results of samples testing of Jiangsu Provincial Malaria Diagnostic Reference Laboratory in 2017, so as to provide the evidence for improving the malaria diagnostic performance in this province.The samples of reported malaria cases in Jiangsu were collected by the provincial reference laboratory (PRL) in 2017. The microscopy and nucleic acid test were performed to confirm the infection of Plasmodium species of each case, while Plasmodium antigen tests (rapid diagnostic test, RDT) were performed as well. The detection results were analyzed among different areas and different species.Totally 242 malaria cases were reported and the samples were collected by PRL in 2017. A total of 239 cases were confirmed Plasmodium infections, including 163 cases of Plasmodium falciparum infection, 21 cases of P. vivax infection, 11 cases of P. malariae infection, 43 cases of P. ovale infection, and 1 case of P. falciparum and P. ovale mixed-infection. The diagnostic coincidence rates of reported malaria case in 13 prefectures with districts were all > 80%, and the total coincidence rate was 88.8%. The species diagnostic coincidence rates of P. falciparum, P. vivax, P. malariae, and P. ovale were 98.8%, 57.1%, 63.6%, and 81.4% respectively, and the detection rates by RDT to those four species infections were 95.7%, 85.0%, 63.6% and 79.1% respectively.In 2017, the malaria diagnostic quality of medical technicians is generally high in Jiangsu Province. However, the diagnostic capacity is slightly different among different regions, and the ability to identify non- P. falciparum parasites remains to be improved. RDT is not ideal for the detection of non-P. falciparum infection. In the current stage of malaria elimination, the malaria diagnostic capacity of technicians in all the sectors should be strengthened and maintained.[摘要] 目的 分析 2017 年江苏省疟疾诊断参比实验室样本检测结果, 为巩固江苏省疟疾诊断水平提供科学依据。方法 由江苏省疟疾诊断参比实验室收集 2017 年疟疾网报病例诊断结果和样本; 对每份病例样本分别采用镜检、核酸检 测复核和疟疾快速诊断试纸条 (RDT) 检测; 比较分析不同地区和不同疟原虫虫种样本检测结果符合情况。结果 2017 年江苏省共有疟疾网报病例 242 例, 经复核确定疟疾病例共 239 例, 其中恶性疟 163 例、间日疟 21 例、三日疟 11 例、卵形 疟 43 例、恶性疟和卵形疟原虫混合感染 1 例。 13 个设区市疟疾网报病例的诊断符合率均> 80%, 总符合率为 88.8%; 恶 性疟原虫、间日疟原虫、三日疟原虫、卵形疟原虫检测符合率分别为 98.8%、 57.1%、 63.6%、 81.4%, RDT 对 4 种疟原虫感染 检出率分别为 95.7%、 85.0%、 63.6%、 79.1%。结论 2017 年江苏省疟疾网报病例诊断质量总体较高, 对非恶性疟人体疟 原虫的虫种鉴别能力有待提高, RDT 对非恶性疟人体疟原虫感染检测效果不理想。在当前消除疟疾阶段, 应加强和保持 各部门的疟疾诊断能力。." @default.
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- W3025101016 date "2018-11-27" @default.
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- W3025101016 title "[Results analysis of Jiangsu Provincial Malaria Diagnostic Reference Laboratory in 2017]." @default.
- W3025101016 doi "https://doi.org/10.16250/j.32.1374.2018267" @default.
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