FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025113694> ?p ?o ?g. }

• W3025113694 endingPage "161" @default.
• W3025113694 startingPage "156" @default.
• W3025113694 abstract "The aim of the study was to explore and identify the relationship between endometrial proliferative/stem cell index and phenotypic characteristics under proliferative processes of endometrium using statistical correlation analysis. The study represents a retrospective research. The coded and depersonalized material data from Acad. N. Kipshidze Central University Clinic was used in the study. 5 study groups (83 cases) were selected from routine histopathology tissue specimens of uterus. Hematoxilyn-eosin technology and immunohistochemistry with markers ki67, CD146, PTEN was performed. The proliferative/stem cell index (PR/ST index) was calculated by the ratio of Ki67-positive cell percentage value divided by CD146-positive cell percentage value. PTEN expression score was evaluated by next scheme - PTEN positive cell numbers <10% - conditional negative, PTEN positive cell numbers 10-50 % - heterogenic, PTEN positive cell numbers >50% - conditional positive. The study showed that, PR/ST index in 1st study group Endometrial Hyperplasia ranges within the interval 15-23, PTEN is diffusely positive with focal heterogeneity 11.1%. 2nd study group Endometrial Dysplasia, the PR/ST index ranges within the interval 16.5-23.3. PTEN heterogeneity is 18.3%, negativity - 6.3%. 3rd study group Endometrioid Carcinoma Grade 1, the PR/ST index ranges between 21.7 and 25.5. PTEN is heterogenic in 35.7% of cases, negative in 14.3% of cases. 4th study group Endometrioid Carcinoma Grade 2, the PR/ST index ranges within the interval 23.2-27.8. PTEN is heterogenic in 43.5% of cases, negative in 30.4% of cases. 5th study group Endometrioid Carcinoma Grade 3, the PR/ST index ranges within the interval 25.8-29.4. PTEN is heterogenic in 33.3% of cases, negative in 41.7% of cases. It was found that, in endometrial hyperplasia and dysplasia cases the PR/ST index do not correlate with phenotypic characteristics, while in the cases of endometrial carcinoma different degrees of malignancy the PR/ST Index and phenotypic characteristics intensely and directly correlates. The high attention should be given to the fact that heterogeneity peak of PTEN expression takes place in the cases of endometrial carcinoma G2, but the negativity of PTEN protein is increasing in parallel with the malignancy increasing process and reaches peak performance in cases of endometrial carcinoma G3." @default.
• W3025113694 created "2020-05-21" @default.
• W3025113694 creator A5001476364 @default.
• W3025113694 creator A5025149219 @default.
• W3025113694 creator A5037110563 @default.
• W3025113694 creator A5082674272 @default.
• W3025113694 date "2018-09-01" @default.
• W3025113694 modified "2023-09-23" @default.
• W3025113694 title "PROLIFERATIVE/STEM CELL INDEX AND PHENOTYPIC CHARACTERISTICS OF PROLIFERATIVE PROCESSES IN ENDOMETRIUM." @default.
• W3025113694 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30358561" @default.
• W3025113694 hasPublicationYear "2018" @default.
• W3025113694 type Work @default.
• W3025113694 sameAs 3025113694 @default.
• W3025113694 citedByCount "0" @default.
• W3025113694 crossrefType "journal-article" @default.
• W3025113694 hasAuthorship W3025113694A5001476364 @default.
• W3025113694 hasAuthorship W3025113694A5025149219 @default.
• W3025113694 hasAuthorship W3025113694A5037110563 @default.
• W3025113694 hasAuthorship W3025113694A5082674272 @default.
• W3025113694 hasConcept C126322002 @default.
• W3025113694 hasConcept C142724271 @default.
• W3025113694 hasConcept C143998085 @default.
• W3025113694 hasConcept C190283241 @default.
• W3025113694 hasConcept C204232928 @default.
• W3025113694 hasConcept C2777546739 @default.
• W3025113694 hasConcept C2777609662 @default.
• W3025113694 hasConcept C2779742232 @default.
• W3025113694 hasConcept C2910938049 @default.
• W3025113694 hasConcept C54355233 @default.
• W3025113694 hasConcept C71924100 @default.
• W3025113694 hasConcept C86554907 @default.
• W3025113694 hasConcept C86803240 @default.
• W3025113694 hasConceptScore W3025113694C126322002 @default.
• W3025113694 hasConceptScore W3025113694C142724271 @default.
• W3025113694 hasConceptScore W3025113694C143998085 @default.
• W3025113694 hasConceptScore W3025113694C190283241 @default.
• W3025113694 hasConceptScore W3025113694C204232928 @default.
• W3025113694 hasConceptScore W3025113694C2777546739 @default.
• W3025113694 hasConceptScore W3025113694C2777609662 @default.
• W3025113694 hasConceptScore W3025113694C2779742232 @default.
• W3025113694 hasConceptScore W3025113694C2910938049 @default.
• W3025113694 hasConceptScore W3025113694C54355233 @default.
• W3025113694 hasConceptScore W3025113694C71924100 @default.
• W3025113694 hasConceptScore W3025113694C86554907 @default.
• W3025113694 hasConceptScore W3025113694C86803240 @default.
• W3025113694 hasIssue "282" @default.
• W3025113694 hasLocation W30251136941 @default.
• W3025113694 hasOpenAccess W3025113694 @default.
• W3025113694 hasPrimaryLocation W30251136941 @default.
• W3025113694 hasRelatedWork W2354946279 @default.
• W3025113694 hasRelatedWork W2358823690 @default.
• W3025113694 hasRelatedWork W2360304879 @default.
• W3025113694 hasRelatedWork W2361436921 @default.
• W3025113694 hasRelatedWork W2362340175 @default.
• W3025113694 hasRelatedWork W2363956645 @default.
• W3025113694 hasRelatedWork W2366268755 @default.
• W3025113694 hasRelatedWork W2368962452 @default.
• W3025113694 hasRelatedWork W2373149611 @default.
• W3025113694 hasRelatedWork W2377997724 @default.
• W3025113694 isParatext "false" @default.
• W3025113694 isRetracted "false" @default.
• W3025113694 magId "3025113694" @default.
• W3025113694 workType "article" @default.