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- W3025148320 endingPage "2285" @default.
- W3025148320 startingPage "2285" @default.
- W3025148320 abstract "The use of light-activated chemical probes to study biological interactions was first discovered in the 1960s, and has since found many applications in studying diseases and gaining deeper insight into various cellular mechanisms involving protein–protein, protein–nucleic acid, protein–ligand (drug, probe), and protein–co-factor interactions, among others. This technique, often referred to as photoaffinity labelling, uses radical precursors that react almost instantaneously to yield spatial and temporal information about the nature of the interaction and the interacting partner(s). This review focuses on the recent advances in chemical biology in the use of benzophenones and diazirines, two of the most commonly known light-activatable radical precursors, with a focus on the last three years, and is intended to provide a solid understanding of their chemical and biological principles and their applications." @default.
- W3025148320 created "2020-05-21" @default.
- W3025148320 creator A5040368325 @default.
- W3025148320 creator A5086079580 @default.
- W3025148320 date "2020-05-13" @default.
- W3025148320 modified "2023-10-01" @default.
- W3025148320 title "Recent Advances in Chemical Biology Using Benzophenones and Diazirines as Radical Precursors" @default.
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