FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025166795> ?p ?o ?g. }

• W3025166795 endingPage "952" @default.
• W3025166795 startingPage "952" @default.
• W3025166795 abstract "Gold nanoparticles (GNPs) emerged as promising antitumor radiosensitizers. However, the complex dependence of GNPs radiosensitization on the irradiation conditions remains unclear. In the present study, we investigated the impacts of the dose rate and photon energy on damage of the pBR322 plasmid DNA exposed to X-rays in the presence of 12 nm, 15 nm, 21 nm, and 26 nm GNPs. The greatest radiosensitization was observed for 26 nm GNPs. The sensitizer enhancement ratio (SER) 2.74 ± 0.61 was observed at 200 kVp with 2.4 mg/mL GNPs. Reduction of X-ray tube voltage to 150 and 100 kVp led to a smaller effect. We demonstrate for the first time that the change of the dose rate differentially influences on radiosensitization by GNPs of various sizes. For 12 nm, an increase in the dose rate from 0.2 to 2.1 Gy/min led to a ~1.13-fold increase in radiosensitization. No differences in the effect of 15 nm GNPs was found within the 0.85–2.1 Gy/min range. For 21 nm and 26 nm GNPs, an enhanced radiosensitization was observed along with the decreased dose rate from 2.1 to 0.2 Gy/min. Thus, GNPs are an effective tool for increasing the efficacy of orthovoltage X-ray exposure. However, careful selection of irradiation conditions is a key prerequisite for optimal radiosensitization efficacy." @default.
• W3025166795 created "2020-05-21" @default.
• W3025166795 creator A5008362644 @default.
• W3025166795 creator A5009359500 @default.
• W3025166795 creator A5014387385 @default.
• W3025166795 creator A5016670215 @default.
• W3025166795 creator A5021261082 @default.
• W3025166795 creator A5032320087 @default.
• W3025166795 creator A5061586706 @default.
• W3025166795 creator A5065749516 @default.
• W3025166795 creator A5068442652 @default.
• W3025166795 creator A5075700503 @default.
• W3025166795 creator A5075949838 @default.
• W3025166795 creator A5090891303 @default.
• W3025166795 date "2020-05-17" @default.
• W3025166795 modified "2023-10-14" @default.
• W3025166795 title "Radiosensitization by Gold Nanoparticles: Impact of the Size, Dose Rate, and Photon Energy" @default.
• W3025166795 cites W1967221154 @default.
• W3025166795 cites W1968256046 @default.
• W3025166795 cites W1976898557 @default.
• W3025166795 cites W1978637377 @default.
• W3025166795 cites W1990041852 @default.
• W3025166795 cites W1990869665 @default.
• W3025166795 cites W1993649338 @default.
• W3025166795 cites W1994718961 @default.
• W3025166795 cites W1998080912 @default.
• W3025166795 cites W2000000511 @default.
• W3025166795 cites W2002285036 @default.
• W3025166795 cites W2021194998 @default.
• W3025166795 cites W2038613867 @default.
• W3025166795 cites W2039558739 @default.
• W3025166795 cites W2041066010 @default.
• W3025166795 cites W2042622201 @default.
• W3025166795 cites W2043389317 @default.
• W3025166795 cites W2057070832 @default.
• W3025166795 cites W2062484120 @default.
• W3025166795 cites W2063056001 @default.
• W3025166795 cites W2063692243 @default.
• W3025166795 cites W2074318483 @default.
• W3025166795 cites W2092171865 @default.
• W3025166795 cites W2100025886 @default.
• W3025166795 cites W2109840939 @default.
• W3025166795 cites W2129998516 @default.
• W3025166795 cites W2130052270 @default.
• W3025166795 cites W2130547709 @default.
• W3025166795 cites W2135173161 @default.
• W3025166795 cites W2136677910 @default.
• W3025166795 cites W2141833256 @default.
• W3025166795 cites W2142483254 @default.
• W3025166795 cites W2143799054 @default.
• W3025166795 cites W2145238798 @default.
• W3025166795 cites W2146804964 @default.
• W3025166795 cites W2148579746 @default.
• W3025166795 cites W2160743259 @default.
• W3025166795 cites W2162255724 @default.
• W3025166795 cites W2167180957 @default.
• W3025166795 cites W2185601963 @default.
• W3025166795 cites W2209394102 @default.
• W3025166795 cites W2295974586 @default.
• W3025166795 cites W2300904217 @default.
• W3025166795 cites W2324603849 @default.
• W3025166795 cites W2335701048 @default.
• W3025166795 cites W2339916725 @default.
• W3025166795 cites W2486254046 @default.
• W3025166795 cites W2603097129 @default.
• W3025166795 cites W2609238343 @default.
• W3025166795 cites W2625047539 @default.
• W3025166795 cites W2743843029 @default.
• W3025166795 cites W2744713071 @default.
• W3025166795 cites W2768044186 @default.
• W3025166795 cites W2768248046 @default.
• W3025166795 cites W2791277913 @default.
• W3025166795 cites W2800396244 @default.
• W3025166795 cites W2804702374 @default.
• W3025166795 cites W2903103544 @default.
• W3025166795 cites W2908718249 @default.
• W3025166795 cites W2913906966 @default.
• W3025166795 cites W2945604143 @default.
• W3025166795 cites W2981124033 @default.
• W3025166795 cites W4211008944 @default.
• W3025166795 cites W4241049853 @default.
• W3025166795 cites W745919197 @default.
• W3025166795 doi "https://doi.org/10.3390/nano10050952" @default.
• W3025166795 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7279506" @default.
• W3025166795 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32429500" @default.
• W3025166795 hasPublicationYear "2020" @default.
• W3025166795 type Work @default.
• W3025166795 sameAs 3025166795 @default.
• W3025166795 citedByCount "27" @default.
• W3025166795 countsByYear W30251667952020 @default.
• W3025166795 countsByYear W30251667952021 @default.
• W3025166795 countsByYear W30251667952022 @default.
• W3025166795 countsByYear W30251667952023 @default.
• W3025166795 crossrefType "journal-article" @default.
• W3025166795 hasAuthorship W3025166795A5008362644 @default.
• W3025166795 hasAuthorship W3025166795A5009359500 @default.
• W3025166795 hasAuthorship W3025166795A5014387385 @default.
• W3025166795 hasAuthorship W3025166795A5016670215 @default.

• next