FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025177564> ?p ?o ?g. }

• W3025177564 abstract "Multidrug resistant Gramnegative (MDRGN) infections are an increasing problem in neonatal intensive care units. The objective of this study was to establish the epidemiological, clinical, microbiological, and evolutionary characteristics of carbapenem-resistant MDRGN infections and the risk factors for them at the Division of Neonatology of a tertiary care hospital.A retrospective cohort study was done in this Division in patients with a documented MDRGN infection between 4/24/2013 and 4/29/2015.Twenty-one patients were included. Their median gestational age and birth weight were 35 weeks and 2070 g, respectively. Eighteen patients (86 %) had a positive blood culture; the most commonly isolated microorganism was Acinetobacter baumannii (17 patients, 81 %), followed by carbapenemase-producing Klebsiella pneumoniae (3 patients, 14 %) and Enterobacter cloacae (1 patient, 5 %).The median age at diagnosis was 28 days and all patients had risk factors for infection, including surgery, assisted mechanical ventilation, parenteral nutrition, central venous line, and antibiotics. The definite antibiotic therapy included colistin in all cases; in combination, in 84 %. Five patients (24 %) died due to the infection. Prematurity and a birth weight < 2000 g were statistically significant risk factors associated with mortality (p = 0.03 and 0.01, respectively).MDRGN infections were observed in patients with predisposing factors. Acinetobacter baumannii was the main etiologic agent. Mortality was high and related to prematurity and a low birth weight.Introducción. Las infecciones por bacilos Gram-negativos multirresistentes (BGN-MR) constituyen un problema creciente en las unidades de cuidado intensivo neonatal. El objetivo del estudio fue conocer las características epidemiológicas, clínicas, microbiológicas, evolutivas y los factores de riesgo de infección por BGN-MR resistentes a carbapenemes en el Servicio de Neonatología de un hospital de alta complejidad. Población y método. Se realizó un estudio de cohorte retrospectivo en dicho Servicio, donde se incluyeron los pacientes con infección documentada por BGN-MR del 24/4/2013 al 29/4/2015. Resultados. Se incluyeron 21 pacientes. La mediana de edad gestacional y peso de nacimiento fue 35 semanas y 2070 gramos, respectivamente. Dieciocho pacientes (86 %) tuvieron hemocultivos positivos y el aislamiento microbiológico más frecuente fue Acinetobacter baumannii (17 pacientes, 81 %), seguido por Klebsiella pneumoniae productora de carbapenemasa (3 pacientes, 14 %) y Enterobacter cloacae (1 paciente, 5 %). La mediana de edad al momento del diagnóstico fue de 28 días y todos tenían factores de riesgo para la infección, como cirugía, asistencia respiratoria mecánica, nutrición parenteral, catéter central y antibióticos. El tratamiento antibiótico definitivo fue colistina en todos los casos, combinado en el 84 %. Cinco pacientes (24 %) fallecieron por la infección. La prematurez y el peso < 2000 g fueron factores de riesgo estadísticamente significativos asociados a la mortalidad (p = 0,03 y 0,01, respectivamente). Conclusión. Las infecciones por BGN-MR se presentaron en pacientes con factores predisponentes. Acinetobacter baumannii fue el primer agente etiológico. La mortalidad fue elevada y relacionada con prematurez y bajo peso al nacer." @default.
• W3025177564 created "2020-05-21" @default.
• W3025177564 creator A5005120909 @default.
• W3025177564 creator A5019493223 @default.
• W3025177564 creator A5021868577 @default.
• W3025177564 creator A5024224059 @default.
• W3025177564 creator A5031341911 @default.
• W3025177564 creator A5034261238 @default.
• W3025177564 creator A5036288458 @default.
• W3025177564 creator A5058587604 @default.
• W3025177564 creator A5062783212 @default.
• W3025177564 date "2019-02-01" @default.
• W3025177564 modified "2023-10-18" @default.
• W3025177564 title "Multidrug resistant Gram-negative infections in neonatology" @default.
• W3025177564 doi "https://doi.org/10.5546/aap.2019.eng.6" @default.
• W3025177564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30652440" @default.
• W3025177564 hasPublicationYear "2019" @default.
• W3025177564 type Work @default.
• W3025177564 sameAs 3025177564 @default.
• W3025177564 citedByCount "7" @default.
• W3025177564 countsByYear W30251775642019 @default.
• W3025177564 countsByYear W30251775642021 @default.
• W3025177564 countsByYear W30251775642023 @default.
• W3025177564 crossrefType "journal-article" @default.
• W3025177564 hasAuthorship W3025177564A5005120909 @default.
• W3025177564 hasAuthorship W3025177564A5019493223 @default.
• W3025177564 hasAuthorship W3025177564A5021868577 @default.
• W3025177564 hasAuthorship W3025177564A5024224059 @default.
• W3025177564 hasAuthorship W3025177564A5031341911 @default.
• W3025177564 hasAuthorship W3025177564A5034261238 @default.
• W3025177564 hasAuthorship W3025177564A5036288458 @default.
• W3025177564 hasAuthorship W3025177564A5058587604 @default.
• W3025177564 hasAuthorship W3025177564A5062783212 @default.
• W3025177564 hasBestOaLocation W30251775641 @default.
• W3025177564 hasConcept C104317684 @default.
• W3025177564 hasConcept C107130276 @default.
• W3025177564 hasConcept C126322002 @default.
• W3025177564 hasConcept C167135981 @default.
• W3025177564 hasConcept C177713679 @default.
• W3025177564 hasConcept C187212893 @default.
• W3025177564 hasConcept C2776315533 @default.
• W3025177564 hasConcept C2777058267 @default.
• W3025177564 hasConcept C2777637488 @default.
• W3025177564 hasConcept C2778376644 @default.
• W3025177564 hasConcept C2779083892 @default.
• W3025177564 hasConcept C2779234561 @default.
• W3025177564 hasConcept C2779259085 @default.
• W3025177564 hasConcept C501593827 @default.
• W3025177564 hasConcept C523546767 @default.
• W3025177564 hasConcept C536800656 @default.
• W3025177564 hasConcept C54355233 @default.
• W3025177564 hasConcept C547475151 @default.
• W3025177564 hasConcept C55493867 @default.
• W3025177564 hasConcept C66322754 @default.
• W3025177564 hasConcept C71924100 @default.
• W3025177564 hasConcept C86803240 @default.
• W3025177564 hasConcept C89423630 @default.
• W3025177564 hasConceptScore W3025177564C104317684 @default.
• W3025177564 hasConceptScore W3025177564C107130276 @default.
• W3025177564 hasConceptScore W3025177564C126322002 @default.
• W3025177564 hasConceptScore W3025177564C167135981 @default.
• W3025177564 hasConceptScore W3025177564C177713679 @default.
• W3025177564 hasConceptScore W3025177564C187212893 @default.
• W3025177564 hasConceptScore W3025177564C2776315533 @default.
• W3025177564 hasConceptScore W3025177564C2777058267 @default.
• W3025177564 hasConceptScore W3025177564C2777637488 @default.
• W3025177564 hasConceptScore W3025177564C2778376644 @default.
• W3025177564 hasConceptScore W3025177564C2779083892 @default.
• W3025177564 hasConceptScore W3025177564C2779234561 @default.
• W3025177564 hasConceptScore W3025177564C2779259085 @default.
• W3025177564 hasConceptScore W3025177564C501593827 @default.
• W3025177564 hasConceptScore W3025177564C523546767 @default.
• W3025177564 hasConceptScore W3025177564C536800656 @default.
• W3025177564 hasConceptScore W3025177564C54355233 @default.
• W3025177564 hasConceptScore W3025177564C547475151 @default.
• W3025177564 hasConceptScore W3025177564C55493867 @default.
• W3025177564 hasConceptScore W3025177564C66322754 @default.
• W3025177564 hasConceptScore W3025177564C71924100 @default.
• W3025177564 hasConceptScore W3025177564C86803240 @default.
• W3025177564 hasConceptScore W3025177564C89423630 @default.
• W3025177564 hasIssue "1" @default.
• W3025177564 hasLocation W30251775641 @default.
• W3025177564 hasLocation W30251775642 @default.
• W3025177564 hasOpenAccess W3025177564 @default.
• W3025177564 hasPrimaryLocation W30251775641 @default.
• W3025177564 hasRelatedWork W1980935798 @default.
• W3025177564 hasRelatedWork W2158317124 @default.
• W3025177564 hasRelatedWork W2395087798 @default.
• W3025177564 hasRelatedWork W2777731155 @default.
• W3025177564 hasRelatedWork W3092431729 @default.
• W3025177564 hasRelatedWork W3099009888 @default.
• W3025177564 hasRelatedWork W3167114812 @default.
• W3025177564 hasRelatedWork W4297200083 @default.
• W3025177564 hasRelatedWork W69272056 @default.
• W3025177564 hasRelatedWork W2225655690 @default.
• W3025177564 hasVolume "117" @default.
• W3025177564 isParatext "false" @default.
• W3025177564 isRetracted "false" @default.
• W3025177564 magId "3025177564" @default.
• W3025177564 workType "article" @default.