Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025207063> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W3025207063 abstract "Detecting life-threatening diseases is a major challenge in biomedicine, as it requires pathogen identication on the molecular level. One promising detection strategy relies on attaching molecular probes to nanoparticles (NPs), which support localised surface plasmon resonance (LSPR). Probe-functionalised NPs can then detect molecular DNA-binding events via a macroscopic change in their optical response. Until now, NP-sensing schemes have been primarily implemented using planar substrates, requiring complex launching techniques and cost-intensive microscopy. An alternative approach adopted in this work involves inltrating optical bres with NPs allowing LSPR excitation and spectral multiplexing within one device. The principle idea relies on probing deposited plasmonic NPs by propagating optical fibre modes, leading to hybrid plasmonic-photonic fibres for biosensing. An important class of innovative bres exploited in this work are microstructured optical bres (MOFs) containing longitudinally invariant microstructures. These structures enable unprecedented adjustment of light matter interaction resulting in a high degree of sensitivity and an optofluidic environment ideally suited for biochemical application. In this thesis optofluidic channels are integrated in direct proximity to the light guiding core, boosting the light-analyte interaction length by orders of magnitude. This concept thus represents a multiscale approach, fundamentally connecting the microscopic level via LSPR-mediated sensing with the macroscopic world using MOFs leading to a novel and unexplored sensor platform. This study shows that combining plasmonic-bre waveguides with microuidics yields a highly integrated, reusable, optouidic interface for efcient refractive index sensing with outlook for DNA diagnostics. This unique combination is extremely attractive from both device and clinical point of view, as the flexible handling of optical fibres principally enables in-vivo application." @default.
- W3025207063 created "2020-05-21" @default.
- W3025207063 creator A5039680383 @default.
- W3025207063 date "2020-01-01" @default.
- W3025207063 modified "2023-09-27" @default.
- W3025207063 title "Plasmonic microstructured optical fibres: an efficient platform towards biosensing" @default.
- W3025207063 doi "https://doi.org/10.22032/dbt.42808" @default.
- W3025207063 hasPublicationYear "2020" @default.
- W3025207063 type Work @default.
- W3025207063 sameAs 3025207063 @default.
- W3025207063 citedByCount "0" @default.
- W3025207063 crossrefType "dissertation" @default.
- W3025207063 hasAuthorship W3025207063A5039680383 @default.
- W3025207063 hasConcept C106847996 @default.
- W3025207063 hasConcept C110879396 @default.
- W3025207063 hasConcept C155672457 @default.
- W3025207063 hasConcept C160756335 @default.
- W3025207063 hasConcept C171250308 @default.
- W3025207063 hasConcept C178790620 @default.
- W3025207063 hasConcept C185592680 @default.
- W3025207063 hasConcept C192562407 @default.
- W3025207063 hasConcept C20788544 @default.
- W3025207063 hasConcept C2777735830 @default.
- W3025207063 hasConcept C32909587 @default.
- W3025207063 hasConcept C49040817 @default.
- W3025207063 hasConcept C85255121 @default.
- W3025207063 hasConceptScore W3025207063C106847996 @default.
- W3025207063 hasConceptScore W3025207063C110879396 @default.
- W3025207063 hasConceptScore W3025207063C155672457 @default.
- W3025207063 hasConceptScore W3025207063C160756335 @default.
- W3025207063 hasConceptScore W3025207063C171250308 @default.
- W3025207063 hasConceptScore W3025207063C178790620 @default.
- W3025207063 hasConceptScore W3025207063C185592680 @default.
- W3025207063 hasConceptScore W3025207063C192562407 @default.
- W3025207063 hasConceptScore W3025207063C20788544 @default.
- W3025207063 hasConceptScore W3025207063C2777735830 @default.
- W3025207063 hasConceptScore W3025207063C32909587 @default.
- W3025207063 hasConceptScore W3025207063C49040817 @default.
- W3025207063 hasConceptScore W3025207063C85255121 @default.
- W3025207063 hasLocation W30252070631 @default.
- W3025207063 hasOpenAccess W3025207063 @default.
- W3025207063 hasPrimaryLocation W30252070631 @default.
- W3025207063 hasRelatedWork W1999435037 @default.
- W3025207063 hasRelatedWork W2077435575 @default.
- W3025207063 hasRelatedWork W2106421725 @default.
- W3025207063 hasRelatedWork W2136878034 @default.
- W3025207063 hasRelatedWork W2155681074 @default.
- W3025207063 hasRelatedWork W2316983003 @default.
- W3025207063 hasRelatedWork W2362954961 @default.
- W3025207063 hasRelatedWork W2556682326 @default.
- W3025207063 hasRelatedWork W2563354156 @default.
- W3025207063 hasRelatedWork W2605818323 @default.
- W3025207063 hasRelatedWork W2611368548 @default.
- W3025207063 hasRelatedWork W2810961157 @default.
- W3025207063 hasRelatedWork W2945082427 @default.
- W3025207063 hasRelatedWork W2961608977 @default.
- W3025207063 hasRelatedWork W2974325008 @default.
- W3025207063 hasRelatedWork W3005772270 @default.
- W3025207063 hasRelatedWork W3011076649 @default.
- W3025207063 hasRelatedWork W3116977891 @default.
- W3025207063 hasRelatedWork W3206690823 @default.
- W3025207063 hasRelatedWork W3212235196 @default.
- W3025207063 isParatext "false" @default.
- W3025207063 isRetracted "false" @default.
- W3025207063 magId "3025207063" @default.
- W3025207063 workType "dissertation" @default.