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- W3025237458 abstract "Central precocious puberty (CPP) results from an early activation of the hypothalamic-pituitary-gonadal (HPG) axis (,). The causes of CPP are heterogeneous, with central nervous system abnormalities being of special interest in boys, while idiopathic etiology is more prevalent among girls (). In the last decade, however, the number of idiopathic cases has diminished thanks to the discovery of mutations in different genes, including KISS1, KISS1R, MKRN3 , and DLK1 (,). GnRH analogs (GnRHa) are the mainstay of treatment for this [...]" @default.
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- W3025237458 date "2020-01-01" @default.
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- W3025237458 title "Challenges in monitoring GnRH analog treatment in central precocious puberty" @default.
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- W3025237458 doi "https://doi.org/10.20945/2359-3997000000241" @default.
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