Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025266366> ?p ?o ?g. }
- W3025266366 abstract "Changes in trabecular micro-architecture are key to our understanding of osteoporosis. Previous work focusing on structure model index (SMI) measurements have concluded that disease progression entails a shift from plates to rods in trabecular bone, but SMI is heavily biased by bone volume fraction. As an alternative to SMI, we proposed the Ellipsoid Factor (EF) as a continuous measure of local trabecular shape between plate-like and rod-like extremes. We investigated the relationship between EF distributions, SMI and bone volume fraction of the trabecular geometry in a murine model of disuse osteoporosis as well as from human vertebrae of differing bone volume fraction. We observed a moderate shift in EF median (at later disease stages in mouse tibia) and EF mode (in the vertebral samples with low bone volume fraction) towards a more rod-like geometry, but not in EF maximum and minimum. These results support the notion that the plate to rod transition does not coincide with the onset of bone loss and is considerably more moderate, when it does occur, than SMI suggests. A variety of local shapes not straightforward to categorise as rod or plate exist in all our trabecular bone samples." @default.
- W3025266366 created "2020-05-21" @default.
- W3025266366 creator A5012842268 @default.
- W3025266366 creator A5023818202 @default.
- W3025266366 creator A5044920884 @default.
- W3025266366 creator A5051138199 @default.
- W3025266366 creator A5078249965 @default.
- W3025266366 creator A5091749009 @default.
- W3025266366 date "2020-05-15" @default.
- W3025266366 modified "2023-10-16" @default.
- W3025266366 title "The plate-to-rod transition in trabecular bone loss is elusive" @default.
- W3025266366 cites W1965930865 @default.
- W3025266366 cites W1979292780 @default.
- W3025266366 cites W1988316565 @default.
- W3025266366 cites W1989511258 @default.
- W3025266366 cites W1990852658 @default.
- W3025266366 cites W1997351324 @default.
- W3025266366 cites W2009144705 @default.
- W3025266366 cites W2022246921 @default.
- W3025266366 cites W2025398368 @default.
- W3025266366 cites W2031772490 @default.
- W3025266366 cites W2040976440 @default.
- W3025266366 cites W2043351120 @default.
- W3025266366 cites W2048733914 @default.
- W3025266366 cites W2052570402 @default.
- W3025266366 cites W2058176263 @default.
- W3025266366 cites W2058798456 @default.
- W3025266366 cites W2065418392 @default.
- W3025266366 cites W2066056548 @default.
- W3025266366 cites W2066749771 @default.
- W3025266366 cites W2068167547 @default.
- W3025266366 cites W2086859574 @default.
- W3025266366 cites W2090288107 @default.
- W3025266366 cites W2093070647 @default.
- W3025266366 cites W2105822769 @default.
- W3025266366 cites W2111064390 @default.
- W3025266366 cites W2121684618 @default.
- W3025266366 cites W2132426860 @default.
- W3025266366 cites W2184832653 @default.
- W3025266366 cites W2256257390 @default.
- W3025266366 cites W2514463807 @default.
- W3025266366 cites W2539420730 @default.
- W3025266366 cites W2604009442 @default.
- W3025266366 cites W2737085999 @default.
- W3025266366 cites W2756145837 @default.
- W3025266366 cites W2760962771 @default.
- W3025266366 cites W2791862747 @default.
- W3025266366 cites W2793837935 @default.
- W3025266366 cites W2910836665 @default.
- W3025266366 cites W2914471594 @default.
- W3025266366 cites W2939141498 @default.
- W3025266366 cites W2984014186 @default.
- W3025266366 cites W2990527602 @default.
- W3025266366 cites W3129752970 @default.
- W3025266366 cites W4230902730 @default.
- W3025266366 cites W4245470104 @default.
- W3025266366 doi "https://doi.org/10.1101/2020.05.14.081042" @default.
- W3025266366 hasPublicationYear "2020" @default.
- W3025266366 type Work @default.
- W3025266366 sameAs 3025266366 @default.
- W3025266366 citedByCount "3" @default.
- W3025266366 countsByYear W30252663662020 @default.
- W3025266366 countsByYear W30252663662021 @default.
- W3025266366 countsByYear W30252663662023 @default.
- W3025266366 crossrefType "posted-content" @default.
- W3025266366 hasAuthorship W3025266366A5012842268 @default.
- W3025266366 hasAuthorship W3025266366A5023818202 @default.
- W3025266366 hasAuthorship W3025266366A5044920884 @default.
- W3025266366 hasAuthorship W3025266366A5051138199 @default.
- W3025266366 hasAuthorship W3025266366A5078249965 @default.
- W3025266366 hasAuthorship W3025266366A5091749009 @default.
- W3025266366 hasBestOaLocation W30252663661 @default.
- W3025266366 hasConcept C105702510 @default.
- W3025266366 hasConcept C121332964 @default.
- W3025266366 hasConcept C134018914 @default.
- W3025266366 hasConcept C136229726 @default.
- W3025266366 hasConcept C159985019 @default.
- W3025266366 hasConcept C185592680 @default.
- W3025266366 hasConcept C192562407 @default.
- W3025266366 hasConcept C20556612 @default.
- W3025266366 hasConcept C2524010 @default.
- W3025266366 hasConcept C2776169692 @default.
- W3025266366 hasConcept C2776541429 @default.
- W3025266366 hasConcept C2777236700 @default.
- W3025266366 hasConcept C2779329777 @default.
- W3025266366 hasConcept C3018268312 @default.
- W3025266366 hasConcept C33923547 @default.
- W3025266366 hasConcept C62520636 @default.
- W3025266366 hasConcept C65590680 @default.
- W3025266366 hasConcept C71924100 @default.
- W3025266366 hasConcept C86803240 @default.
- W3025266366 hasConceptScore W3025266366C105702510 @default.
- W3025266366 hasConceptScore W3025266366C121332964 @default.
- W3025266366 hasConceptScore W3025266366C134018914 @default.
- W3025266366 hasConceptScore W3025266366C136229726 @default.
- W3025266366 hasConceptScore W3025266366C159985019 @default.
- W3025266366 hasConceptScore W3025266366C185592680 @default.
- W3025266366 hasConceptScore W3025266366C192562407 @default.
- W3025266366 hasConceptScore W3025266366C20556612 @default.
- W3025266366 hasConceptScore W3025266366C2524010 @default.