FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025300914> ?p ?o ?g. }

• W3025300914 endingPage "671" @default.
• W3025300914 startingPage "661" @default.
• W3025300914 abstract "Introduction Childhood rheumatic diseases (CRD) are chronic inflammatory conditions, often leading to severe functional impairment and disability. They produce high direct and indirect costs for patients, their families and society overall. Biologic treatment, adalimumab of note, has drastically changed the disease management, significantly decreasing morbidity, over childhood, and eventually lifelong. After 12 years of pediatric experience with adalimumab, safety data resulted of great interest.Areas covered This review summarizes published knowledge about safety of adalimumab in clinical trials and real-life setting studies. Infections and site injection reactions are considered the most frequent adverse events, but the occurrence of second autoimmune diseases as well as malignancy development are the two major concerns of the medical community and families.Expert opinion Adalimumab has revolutionized treatment and prognosis of most of CRD, resulting in good outcomes with highly acceptable safety profile. Number and type of entered adverse events differ from clinical trials and registries, these latter mirroring clinical real life. Different temporal observations and sample cohorts mainly account of this discrepancy. Both randomized clinical trials and real-world data are complementary. Clinical trials coupled with long-term registries will help to improve the evidence-based safety for children with CRD." @default.
• W3025300914 created "2020-05-21" @default.
• W3025300914 creator A5014401271 @default.
• W3025300914 creator A5027713411 @default.
• W3025300914 creator A5079187407 @default.
• W3025300914 creator A5087684196 @default.
• W3025300914 date "2020-05-14" @default.
• W3025300914 modified "2023-09-24" @default.
• W3025300914 title "Safety evaluations of adalimumab for childhood chronic rheumatic diseases" @default.
• W3025300914 cites W1807135488 @default.
• W3025300914 cites W1965840806 @default.
• W3025300914 cites W1969936299 @default.
• W3025300914 cites W1978153301 @default.
• W3025300914 cites W1997106678 @default.
• W3025300914 cites W1998366883 @default.
• W3025300914 cites W2022443996 @default.
• W3025300914 cites W2032008287 @default.
• W3025300914 cites W2035913022 @default.
• W3025300914 cites W2059080840 @default.
• W3025300914 cites W2101762349 @default.
• W3025300914 cites W2120624107 @default.
• W3025300914 cites W2135974703 @default.
• W3025300914 cites W2138181327 @default.
• W3025300914 cites W2140163728 @default.
• W3025300914 cites W2144824470 @default.
• W3025300914 cites W2150411992 @default.
• W3025300914 cites W2167774206 @default.
• W3025300914 cites W2167790577 @default.
• W3025300914 cites W2168707849 @default.
• W3025300914 cites W2278847785 @default.
• W3025300914 cites W2410260085 @default.
• W3025300914 cites W2461656241 @default.
• W3025300914 cites W2550731897 @default.
• W3025300914 cites W2584582619 @default.
• W3025300914 cites W2587731986 @default.
• W3025300914 cites W2608059792 @default.
• W3025300914 cites W2767075485 @default.
• W3025300914 cites W2771193101 @default.
• W3025300914 cites W2778717374 @default.
• W3025300914 cites W2797296870 @default.
• W3025300914 cites W2802186900 @default.
• W3025300914 cites W2883946064 @default.
• W3025300914 cites W2884112445 @default.
• W3025300914 cites W2900115997 @default.
• W3025300914 cites W2905915579 @default.
• W3025300914 cites W2919004480 @default.
• W3025300914 cites W2939848736 @default.
• W3025300914 cites W2944551316 @default.
• W3025300914 cites W2950276571 @default.
• W3025300914 cites W2965147486 @default.
• W3025300914 cites W2965990939 @default.
• W3025300914 cites W2967504655 @default.
• W3025300914 cites W2985758722 @default.
• W3025300914 cites W2990283038 @default.
• W3025300914 cites W4248595528 @default.
• W3025300914 doi "https://doi.org/10.1080/14740338.2020.1763300" @default.
• W3025300914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32406768" @default.
• W3025300914 hasPublicationYear "2020" @default.
• W3025300914 type Work @default.
• W3025300914 sameAs 3025300914 @default.
• W3025300914 citedByCount "8" @default.
• W3025300914 countsByYear W30253009142020 @default.
• W3025300914 countsByYear W30253009142021 @default.
• W3025300914 countsByYear W30253009142022 @default.
• W3025300914 countsByYear W30253009142023 @default.
• W3025300914 crossrefType "journal-article" @default.
• W3025300914 hasAuthorship W3025300914A5014401271 @default.
• W3025300914 hasAuthorship W3025300914A5027713411 @default.
• W3025300914 hasAuthorship W3025300914A5079187407 @default.
• W3025300914 hasAuthorship W3025300914A5087684196 @default.
• W3025300914 hasConcept C126322002 @default.
• W3025300914 hasConcept C177713679 @default.
• W3025300914 hasConcept C187212893 @default.
• W3025300914 hasConcept C197934379 @default.
• W3025300914 hasConcept C2779134260 @default.
• W3025300914 hasConcept C2779399171 @default.
• W3025300914 hasConcept C2780132546 @default.
• W3025300914 hasConcept C535046627 @default.
• W3025300914 hasConcept C71924100 @default.
• W3025300914 hasConceptScore W3025300914C126322002 @default.
• W3025300914 hasConceptScore W3025300914C177713679 @default.
• W3025300914 hasConceptScore W3025300914C187212893 @default.
• W3025300914 hasConceptScore W3025300914C197934379 @default.
• W3025300914 hasConceptScore W3025300914C2779134260 @default.
• W3025300914 hasConceptScore W3025300914C2779399171 @default.
• W3025300914 hasConceptScore W3025300914C2780132546 @default.
• W3025300914 hasConceptScore W3025300914C535046627 @default.
• W3025300914 hasConceptScore W3025300914C71924100 @default.
• W3025300914 hasIssue "6" @default.
• W3025300914 hasLocation W30253009141 @default.
• W3025300914 hasLocation W30253009142 @default.
• W3025300914 hasOpenAccess W3025300914 @default.
• W3025300914 hasPrimaryLocation W30253009141 @default.
• W3025300914 hasRelatedWork W1993780631 @default.
• W3025300914 hasRelatedWork W2056662730 @default.
• W3025300914 hasRelatedWork W2085326056 @default.
• W3025300914 hasRelatedWork W2319635624 @default.
• W3025300914 hasRelatedWork W2440758576 @default.

• next