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- W3025347148 abstract "We studied light-triggered drug releasing performance using surface-engineered nanoporous gold nanoparticles (np-Au NPs). The np-Au NPs were prepared by applying templated pulsed electrochemical deposition for repeated Ag–AgAu nano-segments and subsequent selective Ag phase etching. The resulting np-Au NPs showed characteristic internal porous structure with a gap size of ~15 nm. The surface of the np-Au NPs was rationally modified with mercaptosuccinic acid (MSA) and mercaptopropionic acid (MPA) to control chemical binding force at interface. The MSA modified np-Au NPs showed the best light-triggered drug releasing performance for doxorubicin compared to those of the MPA modified np-Au and the bare np-Au NPs. From in vivo fluorescence imaging study, we found that the MSA modified np-Au NPs efficiently worked for controlled release of doxorubicin with light initiation in a mouse." @default.
- W3025347148 created "2020-05-21" @default.
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- W3025347148 date "2020-08-01" @default.
- W3025347148 modified "2023-10-13" @default.
- W3025347148 title "Surface-engineered nanoporous gold nanoparticles for light-triggered drug release" @default.
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- W3025347148 doi "https://doi.org/10.1016/j.optmat.2020.109985" @default.
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