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- W3025382511 abstract "Transarterial embolization (TAE) can be used to treat unresectable and unablatable liver-dominant metastases from neuroendocrine tumor (NET) and sarcoma. TAE could also potentially be used to treat liver metastases from other primaries, but data on efficacy is limited outside of NET and sarcoma. For hepatocellular carcinoma, NET, and sarcoma, outcomes after TAE and transarterial chemoembolization are similar, suggesting that ischemia is the dominant mechanism causing tumor necrosis. For colorectal cancer liver metastases, transarterial chemoembolization using irinotecan-loaded drug-eluting beads improves overall survival. For NET liver metastases, arterial therapy is generally reserved for patients with progressive liver metastases who are either symptomatic or have a large tumor burden. Asymptomatic small-volume NET liver metastases can be followed and typically do not need to be embolized immediately. Generally, TAE (lobar or selective) is performed starting with 40–120-micron Embosphere microspheres (Merit Medical, South Jordan, UT) (up to five syringes), followed by 100–300-micron Embospheres. The endpoint for embolization is stasis." @default.
- W3025382511 created "2020-05-21" @default.
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- W3025382511 date "2020-01-01" @default.
- W3025382511 modified "2023-10-18" @default.
- W3025382511 title "Embolotherapy for the Management of Liver Malignancies Other Than Hepatocellular Carcinoma" @default.
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- W3025382511 doi "https://doi.org/10.1016/b978-0-323-61204-3.00036-1" @default.
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