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- W3025432855 abstract "Surrogate biomarkers of liver fibrosis developed in tertiary care are increasingly used in general populations. We evaluated the association between liver stiffness (LS) and five continuous (AST/ALT, APRI, Forns Index, FIB-4, GGT) and two discrete biomarkers (BARD, BAAT) in a general population. 636 (29%) of the 2159 citizens of the Bagnacavallo Study had LS measured by transient elastography. Using linear regression with univariate multiple imputation, we evaluated the association of LS with the above biomarkers in the total sample of 2159 citizens. The mean change of LS between the 5th and 95th internal percentile of any continuous biomarker was ≤1 kPa. The mean change of LS between scores 0 and 3 of BARD and scores 0 and ≥3 of BAAT was >1 kPa but of doubtful clinical relevance. We found a modest association between LS and seven biomarkers of liver fibrosis in a general population." @default.
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- W3025432855 date "2020-07-01" @default.
- W3025432855 modified "2023-10-18" @default.
- W3025432855 title "Is there an association between commonly employed biomarkers of liver fibrosis and liver stiffness in the general population?" @default.
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- W3025432855 doi "https://doi.org/10.1016/j.aohep.2020.04.003" @default.
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