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- W3025509630 abstract "In this study, a range of oxamide ligands were synthesized by the reaction of amines with oxalyl chloride in basic medium. Spectroscopic and analytical techniques such as IR, 1H-NMR and ESI-MS techniques were used for characterization of the synthesized oxamides. The synthesized oxamides were screened for Lipoxygenase inhibition. Biological screening revealed that the oxamides possessed good lipoxygenase inhibition activities, whereas, the unsubstituted oxamide did not show any distinct lipoxygenase inhibition activity. Molecular docking studies of the oxamides were also carried out for lipoxygenase inhibition. The results obtained from molecular docking were well correlated with the empirical data." @default.
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- W3025509630 date "2019-05-01" @default.
- W3025509630 modified "2023-09-26" @default.
- W3025509630 title "Synthesis, lipoxygenase inhibition activity and molecular docking of oxamide derivative." @default.
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