Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025561312> ?p ?o ?g. }
- W3025561312 endingPage "1458" @default.
- W3025561312 startingPage "1448" @default.
- W3025561312 abstract "Background and purpose The aim was to investigate whether female reproductive factors are associated with dementia. Methods In all, 4 696 633 post‐menopausal women without dementia were identified using the Korean National Health Insurance System database. Data on reproductive factors were collected using a self‐administered questionnaire. Dementia was determined using dementia diagnosis codes and anti‐dementia drug prescription. Cox proportional hazards regression was conducted to assess the hazard ratio (HR) for dementia according to reproductive factors. Results During a median follow‐up of 5.74 years, there were 212 227 new cases of all‐cause dementia (4.5%), 162 901 cases of Alzheimer’s disease (3.5%) and 24 029 cases of vascular dementia (0.5%). The HR of dementia was 1.15 [95% confidence interval (CI) 1.03–1.16] for menarcheal age ≥17 years compared with menarcheal age 13–14 years, 0.79 (0.77–0.81) for menopausal age ≥55 years compared with menopausal age <40 years, and 0.81 (0.79–0.82) for fertility duration ≥40 years compared with fertility duration <30 years. Whilst being of parity one (HR 0.89, 95% CI 0.85–0.94) and breastfeeding <6 months (HR 0.92, 95% CI 0.88–0.95) was associated with lower risk of dementia, being of parity two or more (HR 1.04, 95% CI 0.99–1.05) and breastfeeding ≥12 months (HR 1.14, 95% CI 1.01–1.07) was associated with a higher risk of dementia than women without parity or breastfeeding history. Use of hormone replacement therapy and oral contraceptives independently reduced the dementia risk by 15% and 10%, respectively. Conclusions Female reproductive factors are independent risk factors for dementia incidence, with higher risk associated with shorter lifetime endogenous estrogen exposure." @default.
- W3025561312 created "2020-05-21" @default.
- W3025561312 creator A5001679413 @default.
- W3025561312 creator A5011785496 @default.
- W3025561312 creator A5030772666 @default.
- W3025561312 creator A5031787859 @default.
- W3025561312 creator A5044430956 @default.
- W3025561312 creator A5047846074 @default.
- W3025561312 creator A5057040960 @default.
- W3025561312 creator A5065502713 @default.
- W3025561312 creator A5086029573 @default.
- W3025561312 date "2020-06-13" @default.
- W3025561312 modified "2023-10-18" @default.
- W3025561312 title "Female reproductive factors and the risk of dementia: a nationwide cohort study" @default.
- W3025561312 cites W1846943659 @default.
- W3025561312 cites W1947395210 @default.
- W3025561312 cites W1964829427 @default.
- W3025561312 cites W1968249925 @default.
- W3025561312 cites W1975275132 @default.
- W3025561312 cites W1978663099 @default.
- W3025561312 cites W1983271288 @default.
- W3025561312 cites W1994320218 @default.
- W3025561312 cites W1996249619 @default.
- W3025561312 cites W2002537893 @default.
- W3025561312 cites W2002580984 @default.
- W3025561312 cites W2002844489 @default.
- W3025561312 cites W2009343153 @default.
- W3025561312 cites W2016117684 @default.
- W3025561312 cites W2017844489 @default.
- W3025561312 cites W2023667812 @default.
- W3025561312 cites W2026838410 @default.
- W3025561312 cites W2028547764 @default.
- W3025561312 cites W2031525359 @default.
- W3025561312 cites W2038166770 @default.
- W3025561312 cites W2039280477 @default.
- W3025561312 cites W2041123499 @default.
- W3025561312 cites W2055069595 @default.
- W3025561312 cites W2055090365 @default.
- W3025561312 cites W2056787227 @default.
- W3025561312 cites W2075650045 @default.
- W3025561312 cites W2083675031 @default.
- W3025561312 cites W2083963228 @default.
- W3025561312 cites W2102841629 @default.
- W3025561312 cites W2111783631 @default.
- W3025561312 cites W2112457093 @default.
- W3025561312 cites W2119691301 @default.
- W3025561312 cites W2123652060 @default.
- W3025561312 cites W2131266318 @default.
- W3025561312 cites W2133974148 @default.
- W3025561312 cites W2169308317 @default.
- W3025561312 cites W2210076914 @default.
- W3025561312 cites W2281149080 @default.
- W3025561312 cites W2341026696 @default.
- W3025561312 cites W2378845778 @default.
- W3025561312 cites W2465155672 @default.
- W3025561312 cites W2588583572 @default.
- W3025561312 cites W2773143320 @default.
- W3025561312 cites W2783735153 @default.
- W3025561312 cites W4246835056 @default.
- W3025561312 cites W578040726 @default.
- W3025561312 doi "https://doi.org/10.1111/ene.14315" @default.
- W3025561312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32396982" @default.
- W3025561312 hasPublicationYear "2020" @default.
- W3025561312 type Work @default.
- W3025561312 sameAs 3025561312 @default.
- W3025561312 citedByCount "35" @default.
- W3025561312 countsByYear W30255613122021 @default.
- W3025561312 countsByYear W30255613122022 @default.
- W3025561312 countsByYear W30255613122023 @default.
- W3025561312 crossrefType "journal-article" @default.
- W3025561312 hasAuthorship W3025561312A5001679413 @default.
- W3025561312 hasAuthorship W3025561312A5011785496 @default.
- W3025561312 hasAuthorship W3025561312A5030772666 @default.
- W3025561312 hasAuthorship W3025561312A5031787859 @default.
- W3025561312 hasAuthorship W3025561312A5044430956 @default.
- W3025561312 hasAuthorship W3025561312A5047846074 @default.
- W3025561312 hasAuthorship W3025561312A5057040960 @default.
- W3025561312 hasAuthorship W3025561312A5065502713 @default.
- W3025561312 hasAuthorship W3025561312A5086029573 @default.
- W3025561312 hasConcept C126322002 @default.
- W3025561312 hasConcept C131872663 @default.
- W3025561312 hasConcept C187212893 @default.
- W3025561312 hasConcept C201903717 @default.
- W3025561312 hasConcept C207103383 @default.
- W3025561312 hasConcept C2776283161 @default.
- W3025561312 hasConcept C2777952318 @default.
- W3025561312 hasConcept C2779134260 @default.
- W3025561312 hasConcept C2779483572 @default.
- W3025561312 hasConcept C2908647359 @default.
- W3025561312 hasConcept C44249647 @default.
- W3025561312 hasConcept C50382708 @default.
- W3025561312 hasConcept C518429986 @default.
- W3025561312 hasConcept C71924100 @default.
- W3025561312 hasConcept C72563966 @default.
- W3025561312 hasConcept C99454951 @default.
- W3025561312 hasConceptScore W3025561312C126322002 @default.
- W3025561312 hasConceptScore W3025561312C131872663 @default.
- W3025561312 hasConceptScore W3025561312C187212893 @default.