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- W3025574725 endingPage "12" @default.
- W3025574725 startingPage "12" @default.
- W3025574725 abstract ": The human elbow is a complex joint that is essential for activities of daily living requiring the upper extremities; however, this complexity generates significant challenges when considering its response to injury and management of treatment. The current understanding of elbow injury and pathologies lags behind that of other joints and musculoskeletal tissues. Most research on the elbow joint is mainly focused on the late-disease stages when irreversible damage has occurred. Consequentially, the specific contribution and relative time course of different elbow tissues in disease progression, as well as optimized approaches for treating such conditions, remains largely unknown. Given the challenge of studying elbow pathologies in humans, preclinical models can serve as ideal alternatives. However, a limited number of preclinical models exist to investigate elbow injury and pathology. This review highlights significant clinical elbow diseases and the preclinical models currently available to recapitulate these diseases, while also providing recommendations for the development of future preclinical models. Overall, this review will serve as a guide for preclinical models studying injuries and pathologies of the elbow, with the long-term goal of developing novel intervention strategies to improve the treatment of elbow diseases in human patients." @default.
- W3025574725 created "2020-05-21" @default.
- W3025574725 creator A5032196334 @default.
- W3025574725 creator A5035877664 @default.
- W3025574725 creator A5044183247 @default.
- W3025574725 date "2021-01-01" @default.
- W3025574725 modified "2023-09-23" @default.
- W3025574725 title "Preclinical models of elbow injury and pathology" @default.
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