FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025651963> ?p ?o ?g. }

• W3025651963 endingPage "104451" @default.
• W3025651963 startingPage "104451" @default.
• W3025651963 abstract "Diffuse large B-cell lymphoma (DLBCL) is a leading cause of non-Hodgkin lymphomas. Existing researches have verified that long non-coding RNAs (lncRNAs) play crucial roles in the development of DLBCL, nevertheless, whether lncRNA OR3A4 has influences on the progression of DCBCL needs further exploration. In our study, it was revealed that the expression of OR3A4 was upregulated in DLBCL tumors and cell lines, and patients with high OR3A4 expression suffered from poor prognosis. Knockdown of OR3A4 suppressed cell proliferation and promoted cell apoptosis in DLBCL. Moreover, knockdown of OR3A4 inactivated Wnt/β-catenin signaling pathway, and Riluzole treatment could partially rescue the inhibitive effect of OR3A4 silencing on DLBCL cell proliferation. Furthermore, FOXM1 expression was discovered to be upregulated in DLBCL tissues, and it positively modulated the expression of OR3A4 at transcriptional leve. It was also revealed that FOXM1 knockdown inactivated Wnt/β-catenin signaling pathway. Finally, rescue assays confirmed that OR3A4 overexpression or the treatment of Riluzole could partially countervail the inhibitive effect of FOXM1 silencing on DLBCL progression. Taken together, FOXM1-induced upregulation of OR3A4 enhances the occurrence of DLBCL via Wnt/β-catenin signaling pathway." @default.
• W3025651963 created "2020-05-21" @default.
• W3025651963 creator A5038690804 @default.
• W3025651963 creator A5049842580 @default.
• W3025651963 creator A5088860177 @default.
• W3025651963 date "2020-08-01" @default.
• W3025651963 modified "2023-10-18" @default.
• W3025651963 title "FOXM1-induced upregulation of lncRNA OR3A4 promotes the progression of diffuse large B-cell lymphoma via Wnt/β-catenin signaling pathway" @default.
• W3025651963 cites W1593004859 @default.
• W3025651963 cites W1994099480 @default.
• W3025651963 cites W1995586052 @default.
• W3025651963 cites W2006419043 @default.
• W3025651963 cites W2051005556 @default.
• W3025651963 cites W2112713769 @default.
• W3025651963 cites W2154345686 @default.
• W3025651963 cites W2300667207 @default.
• W3025651963 cites W2407520682 @default.
• W3025651963 cites W2460073819 @default.
• W3025651963 cites W2498372051 @default.
• W3025651963 cites W2530390823 @default.
• W3025651963 cites W2532643640 @default.
• W3025651963 cites W2586687042 @default.
• W3025651963 cites W2596370052 @default.
• W3025651963 cites W2607068081 @default.
• W3025651963 cites W2621361823 @default.
• W3025651963 cites W2743755800 @default.
• W3025651963 cites W2743760745 @default.
• W3025651963 cites W2748435474 @default.
• W3025651963 cites W2760159932 @default.
• W3025651963 cites W2763621202 @default.
• W3025651963 cites W2792567388 @default.
• W3025651963 cites W2797672081 @default.
• W3025651963 cites W2809413985 @default.
• W3025651963 cites W2889622422 @default.
• W3025651963 cites W2912676549 @default.
• W3025651963 cites W2921225334 @default.
• W3025651963 cites W2936996199 @default.
• W3025651963 cites W2961823581 @default.
• W3025651963 doi "https://doi.org/10.1016/j.yexmp.2020.104451" @default.
• W3025651963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32417392" @default.
• W3025651963 hasPublicationYear "2020" @default.
• W3025651963 type Work @default.
• W3025651963 sameAs 3025651963 @default.
• W3025651963 citedByCount "15" @default.
• W3025651963 countsByYear W30256519632020 @default.
• W3025651963 countsByYear W30256519632021 @default.
• W3025651963 countsByYear W30256519632022 @default.
• W3025651963 countsByYear W30256519632023 @default.
• W3025651963 crossrefType "journal-article" @default.
• W3025651963 hasAuthorship W3025651963A5038690804 @default.
• W3025651963 hasAuthorship W3025651963A5049842580 @default.
• W3025651963 hasAuthorship W3025651963A5088860177 @default.
• W3025651963 hasConcept C104317684 @default.
• W3025651963 hasConcept C119056186 @default.
• W3025651963 hasConcept C127561419 @default.
• W3025651963 hasConcept C137620995 @default.
• W3025651963 hasConcept C170240278 @default.
• W3025651963 hasConcept C173396325 @default.
• W3025651963 hasConcept C190283241 @default.
• W3025651963 hasConcept C203014093 @default.
• W3025651963 hasConcept C22615655 @default.
• W3025651963 hasConcept C2778559949 @default.
• W3025651963 hasConcept C2779338263 @default.
• W3025651963 hasConcept C30145163 @default.
• W3025651963 hasConcept C502942594 @default.
• W3025651963 hasConcept C54009773 @default.
• W3025651963 hasConcept C54355233 @default.
• W3025651963 hasConcept C62112901 @default.
• W3025651963 hasConcept C62478195 @default.
• W3025651963 hasConcept C81885089 @default.
• W3025651963 hasConcept C86803240 @default.
• W3025651963 hasConcept C95444343 @default.
• W3025651963 hasConceptScore W3025651963C104317684 @default.
• W3025651963 hasConceptScore W3025651963C119056186 @default.
• W3025651963 hasConceptScore W3025651963C127561419 @default.
• W3025651963 hasConceptScore W3025651963C137620995 @default.
• W3025651963 hasConceptScore W3025651963C170240278 @default.
• W3025651963 hasConceptScore W3025651963C173396325 @default.
• W3025651963 hasConceptScore W3025651963C190283241 @default.
• W3025651963 hasConceptScore W3025651963C203014093 @default.
• W3025651963 hasConceptScore W3025651963C22615655 @default.
• W3025651963 hasConceptScore W3025651963C2778559949 @default.
• W3025651963 hasConceptScore W3025651963C2779338263 @default.
• W3025651963 hasConceptScore W3025651963C30145163 @default.
• W3025651963 hasConceptScore W3025651963C502942594 @default.
• W3025651963 hasConceptScore W3025651963C54009773 @default.
• W3025651963 hasConceptScore W3025651963C54355233 @default.
• W3025651963 hasConceptScore W3025651963C62112901 @default.
• W3025651963 hasConceptScore W3025651963C62478195 @default.
• W3025651963 hasConceptScore W3025651963C81885089 @default.
• W3025651963 hasConceptScore W3025651963C86803240 @default.
• W3025651963 hasConceptScore W3025651963C95444343 @default.
• W3025651963 hasLocation W30256519631 @default.
• W3025651963 hasLocation W30256519632 @default.
• W3025651963 hasOpenAccess W3025651963 @default.
• W3025651963 hasPrimaryLocation W30256519631 @default.
• W3025651963 hasRelatedWork W1482045571 @default.
• W3025651963 hasRelatedWork W2009139774 @default.

• next