FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025657645> ?p ?o ?g. }

• W3025657645 abstract "Salmonella enterica is the leading foodborne pathogen associated with outbreaks involving low-moisture foods (LMFs). However, the genes involved in Salmonella's long-term survival on LMFs remain poorly characterized. In this study, in-shell pistachios were inoculated with Tn5-based mutant libraries of S. Enteritidis P125109, S. Typhimurium 14028s, and S. Newport C4.2 at approximate 108 CFU/g and stored at 25°C. Transposon sequencing analysis (Tn-seq) was then employed to determine the relative abundance of each Tn5 insertion site immediately after inoculation (T0), after drying (T1), and at 120 days (T120). In S. Enteritidis, S. Typhimurium, and S. Newport mutant libraries, the relative abundance of 51, 80, and 101 Tn5 insertion sites, respectively, was significantly lower at T1 compared to T0, while in libraries of S. Enteritidis and S. Typhimurium the relative abundance of 42 and 68 Tn5 insertion sites, respectively, was significantly lower at T120 compared to T1. Tn5 insertion sites with reduced relative abundance in this competition assay were localized in DNA repair, lipopolysaccharide biosynthesis and stringent response genes. Twelve genes among those under strong negative selection in the competition assay were selected for further study. Whole gene deletion mutants in ten of these genes, sspA, barA, uvrB, damX, rfbD, uvrY, lrhA, yifE, rbsR, and ompR, were impaired for individual survival on pistachios. The findings highlight the value of combined mutagenesis and sequencing to identify novel genes important for the survival of Salmonella in low-moisture foods." @default.
• W3025657645 created "2020-05-21" @default.
• W3025657645 creator A5018473151 @default.
• W3025657645 creator A5039477629 @default.
• W3025657645 creator A5047651327 @default.
• W3025657645 creator A5054868164 @default.
• W3025657645 creator A5059686326 @default.
• W3025657645 creator A5083233960 @default.
• W3025657645 date "2020-05-15" @default.
• W3025657645 modified "2023-10-10" @default.
• W3025657645 title "Identification of Novel Genes Mediating Survival of Salmonella on Low-Moisture Foods via Transposon Sequencing Analysis" @default.
• W3025657645 cites W148602700 @default.
• W3025657645 cites W1521759491 @default.
• W3025657645 cites W1558570590 @default.
• W3025657645 cites W1676036532 @default.
• W3025657645 cites W1966625228 @default.
• W3025657645 cites W1973608434 @default.
• W3025657645 cites W1984390417 @default.
• W3025657645 cites W1985324647 @default.
• W3025657645 cites W1987191095 @default.
• W3025657645 cites W2020775251 @default.
• W3025657645 cites W2025244182 @default.
• W3025657645 cites W2030426089 @default.
• W3025657645 cites W2038655927 @default.
• W3025657645 cites W2042190325 @default.
• W3025657645 cites W2042338530 @default.
• W3025657645 cites W2044924241 @default.
• W3025657645 cites W2048448010 @default.
• W3025657645 cites W2049588263 @default.
• W3025657645 cites W2050588463 @default.
• W3025657645 cites W2063430028 @default.
• W3025657645 cites W2073360824 @default.
• W3025657645 cites W2078446890 @default.
• W3025657645 cites W2078712330 @default.
• W3025657645 cites W2091915244 @default.
• W3025657645 cites W2092620403 @default.
• W3025657645 cites W2106673954 @default.
• W3025657645 cites W2112194896 @default.
• W3025657645 cites W2126040811 @default.
• W3025657645 cites W2127256267 @default.
• W3025657645 cites W2136118644 @default.
• W3025657645 cites W2138439355 @default.
• W3025657645 cites W2141891445 @default.
• W3025657645 cites W2142603394 @default.
• W3025657645 cites W2144573392 @default.
• W3025657645 cites W2147657950 @default.
• W3025657645 cites W2148258370 @default.
• W3025657645 cites W2150800566 @default.
• W3025657645 cites W2151689343 @default.
• W3025657645 cites W2153153456 @default.
• W3025657645 cites W2155361726 @default.
• W3025657645 cites W2158408911 @default.
• W3025657645 cites W2159845888 @default.
• W3025657645 cites W2162109899 @default.
• W3025657645 cites W2166742266 @default.
• W3025657645 cites W2179438025 @default.
• W3025657645 cites W2236861089 @default.
• W3025657645 cites W2326857875 @default.
• W3025657645 cites W2328090054 @default.
• W3025657645 cites W2335565141 @default.
• W3025657645 cites W2473907142 @default.
• W3025657645 cites W2509569476 @default.
• W3025657645 cites W2526226643 @default.
• W3025657645 cites W2528992040 @default.
• W3025657645 cites W2559414299 @default.
• W3025657645 cites W2566232961 @default.
• W3025657645 cites W2752784701 @default.
• W3025657645 cites W2767577424 @default.
• W3025657645 cites W2787464224 @default.
• W3025657645 cites W2803643922 @default.
• W3025657645 cites W2810986407 @default.
• W3025657645 cites W2923467062 @default.
• W3025657645 cites W4230983948 @default.
• W3025657645 cites W4243497327 @default.
• W3025657645 doi "https://doi.org/10.3389/fmicb.2020.00726" @default.
• W3025657645 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7242855" @default.
• W3025657645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32499760" @default.
• W3025657645 hasPublicationYear "2020" @default.
• W3025657645 type Work @default.
• W3025657645 sameAs 3025657645 @default.
• W3025657645 citedByCount "13" @default.
• W3025657645 countsByYear W30256576452020 @default.
• W3025657645 countsByYear W30256576452021 @default.
• W3025657645 countsByYear W30256576452022 @default.
• W3025657645 countsByYear W30256576452023 @default.
• W3025657645 crossrefType "journal-article" @default.
• W3025657645 hasAuthorship W3025657645A5018473151 @default.
• W3025657645 hasAuthorship W3025657645A5039477629 @default.
• W3025657645 hasAuthorship W3025657645A5047651327 @default.
• W3025657645 hasAuthorship W3025657645A5054868164 @default.
• W3025657645 hasAuthorship W3025657645A5059686326 @default.
• W3025657645 hasAuthorship W3025657645A5083233960 @default.
• W3025657645 hasBestOaLocation W30256576451 @default.
• W3025657645 hasConcept C104317684 @default.
• W3025657645 hasConcept C116834253 @default.
• W3025657645 hasConcept C141231307 @default.
• W3025657645 hasConcept C150903083 @default.
• W3025657645 hasConcept C2781065037 @default.
• W3025657645 hasConcept C4918238 @default.
• W3025657645 hasConcept C51679486 @default.

• next