Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025665758> ?p ?o ?g. }
- W3025665758 abstract "Caffeine is widely used in preterm neonates suffering from apnea of prematurity (AOP), and it has become one of the most frequently prescribed medications in neonatal intensive care units. Goal of this study is to investigate how caffeine citrate treatment affects sleep-wake behavior in preterm neonates. The observational study consists of 64 preterm neonates during their first 5 days of life with gestational age (GA) <32 weeks or very low birthweight of < 1500 g. A total of 52 patients treated with caffeine citrate and 12 patients without caffeine citrate were included. Sleep-wake behavior was scored in three stages: active sleep, quiet sleep, and wakefulness. Individual caffeine concentration of every neonate was simulated with a pharmacokinetic model. In neonates with GA ≥ 28 weeks, wakefulness increased and active sleep decreased with increasing caffeine concentrations, whereas quiet sleep remained unchanged. In neonates with GA < 28 weeks, no clear caffeine effects on sleep-wake behavior could be demonstrated. Caffeine increases fraction of wakefulness, alertness, and most probably also arousability at cost of active but not quiet sleep in preterm neonates. As such, caffeine should therefore not affect time for physical and cerebral regeneration during sleep in preterm neonates." @default.
- W3025665758 created "2020-05-21" @default.
- W3025665758 creator A5004280057 @default.
- W3025665758 creator A5010483604 @default.
- W3025665758 creator A5020061820 @default.
- W3025665758 creator A5022529558 @default.
- W3025665758 creator A5038873896 @default.
- W3025665758 creator A5056468783 @default.
- W3025665758 creator A5061053067 @default.
- W3025665758 date "2020-05-15" @default.
- W3025665758 modified "2023-10-15" @default.
- W3025665758 title "Caffeine preserves quiet sleep in preterm neonates" @default.
- W3025665758 cites W1628292530 @default.
- W3025665758 cites W1972232046 @default.
- W3025665758 cites W1999535411 @default.
- W3025665758 cites W2000293202 @default.
- W3025665758 cites W2001013152 @default.
- W3025665758 cites W2001420919 @default.
- W3025665758 cites W2020803142 @default.
- W3025665758 cites W2028928043 @default.
- W3025665758 cites W2052449009 @default.
- W3025665758 cites W2053269045 @default.
- W3025665758 cites W2062614689 @default.
- W3025665758 cites W2063267655 @default.
- W3025665758 cites W2068861236 @default.
- W3025665758 cites W2073142648 @default.
- W3025665758 cites W2075649075 @default.
- W3025665758 cites W2083143366 @default.
- W3025665758 cites W2090267724 @default.
- W3025665758 cites W2095797524 @default.
- W3025665758 cites W2114235313 @default.
- W3025665758 cites W2130249957 @default.
- W3025665758 cites W2142638823 @default.
- W3025665758 cites W2159615203 @default.
- W3025665758 cites W2323145572 @default.
- W3025665758 cites W2346907223 @default.
- W3025665758 cites W2395180239 @default.
- W3025665758 cites W2416402053 @default.
- W3025665758 cites W2528451980 @default.
- W3025665758 cites W2551986483 @default.
- W3025665758 cites W2609228496 @default.
- W3025665758 cites W2609946048 @default.
- W3025665758 cites W2767831806 @default.
- W3025665758 cites W2768937796 @default.
- W3025665758 cites W2945011557 @default.
- W3025665758 cites W4294305256 @default.
- W3025665758 cites W95742513 @default.
- W3025665758 doi "https://doi.org/10.1002/prp2.596" @default.
- W3025665758 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7227120" @default.
- W3025665758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32412185" @default.
- W3025665758 hasPublicationYear "2020" @default.
- W3025665758 type Work @default.
- W3025665758 sameAs 3025665758 @default.
- W3025665758 citedByCount "8" @default.
- W3025665758 countsByYear W30256657582020 @default.
- W3025665758 countsByYear W30256657582021 @default.
- W3025665758 countsByYear W30256657582022 @default.
- W3025665758 countsByYear W30256657582023 @default.
- W3025665758 crossrefType "journal-article" @default.
- W3025665758 hasAuthorship W3025665758A5004280057 @default.
- W3025665758 hasAuthorship W3025665758A5010483604 @default.
- W3025665758 hasAuthorship W3025665758A5020061820 @default.
- W3025665758 hasAuthorship W3025665758A5022529558 @default.
- W3025665758 hasAuthorship W3025665758A5038873896 @default.
- W3025665758 hasAuthorship W3025665758A5056468783 @default.
- W3025665758 hasAuthorship W3025665758A5061053067 @default.
- W3025665758 hasBestOaLocation W30256657581 @default.
- W3025665758 hasConcept C111919701 @default.
- W3025665758 hasConcept C118552586 @default.
- W3025665758 hasConcept C121332964 @default.
- W3025665758 hasConcept C15744967 @default.
- W3025665758 hasConcept C2775841894 @default.
- W3025665758 hasConcept C2777185736 @default.
- W3025665758 hasConcept C2778500429 @default.
- W3025665758 hasConcept C41008148 @default.
- W3025665758 hasConcept C42219234 @default.
- W3025665758 hasConcept C62520636 @default.
- W3025665758 hasConcept C71924100 @default.
- W3025665758 hasConceptScore W3025665758C111919701 @default.
- W3025665758 hasConceptScore W3025665758C118552586 @default.
- W3025665758 hasConceptScore W3025665758C121332964 @default.
- W3025665758 hasConceptScore W3025665758C15744967 @default.
- W3025665758 hasConceptScore W3025665758C2775841894 @default.
- W3025665758 hasConceptScore W3025665758C2777185736 @default.
- W3025665758 hasConceptScore W3025665758C2778500429 @default.
- W3025665758 hasConceptScore W3025665758C41008148 @default.
- W3025665758 hasConceptScore W3025665758C42219234 @default.
- W3025665758 hasConceptScore W3025665758C62520636 @default.
- W3025665758 hasConceptScore W3025665758C71924100 @default.
- W3025665758 hasFunder F4320320924 @default.
- W3025665758 hasIssue "3" @default.
- W3025665758 hasLocation W30256657581 @default.
- W3025665758 hasLocation W30256657582 @default.
- W3025665758 hasLocation W30256657583 @default.
- W3025665758 hasOpenAccess W3025665758 @default.
- W3025665758 hasPrimaryLocation W30256657581 @default.
- W3025665758 hasRelatedWork W1898791594 @default.
- W3025665758 hasRelatedWork W2036981778 @default.
- W3025665758 hasRelatedWork W2419532383 @default.
- W3025665758 hasRelatedWork W2474960741 @default.