FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025704615> ?p ?o ?g. }

• W3025704615 endingPage "2353" @default.
• W3025704615 startingPage "2353" @default.
• W3025704615 abstract "The prevalence of some chronic diseases, such as cancer or neurodegenerative disorders, differs between sexes. Animal models provide an important tool to adopt potential therapies from preclinical studies to humans. Laboratory rats are the most popular animals in toxicology, neurobehavioral, or cancer research. Our study aimed to reveal the basic differences in blood metabolome (amino acids, biogenic amines, and acylcarnitines) of the adult male (n = 10) and female (n = 10) Wistar rats. Partial least square-discrimination analysis (PLS-DA) and a variance im portance in projection (VIP) score was used to identify the key sex-specific metabolites. All groups of metabolites, as the main markers of energy metabolism, showed a significant sex-dependent pattern. The most important features calculated in PLS-DA according to VIP score were free carnitine (C0), tyrosine (Tyr), and acylcarnitine C5-OH. While aromatic amino acids, such as Tyr and phenylalanine (Phe), were significantly elevated in the blood plasma of males, tryptophan (Trp) was found in higher levels in the blood plasma of females. Besides, significant sex-related changes in urea cycle were found. Our study provides an important insight into sex-specific differences in energy metabolism in rats and indicates that further studies should consider sex as the main aspect in design and data interpretation." @default.
• W3025704615 created "2020-05-21" @default.
• W3025704615 creator A5023151211 @default.
• W3025704615 creator A5034929369 @default.
• W3025704615 creator A5042569868 @default.
• W3025704615 creator A5043001329 @default.
• W3025704615 creator A5045705864 @default.
• W3025704615 creator A5047927390 @default.
• W3025704615 creator A5058920839 @default.
• W3025704615 creator A5065873883 @default.
• W3025704615 creator A5083806306 @default.
• W3025704615 date "2020-05-18" @default.
• W3025704615 modified "2023-10-16" @default.
• W3025704615 title "Sexual Dimorphism in Energy Metabolism of Wistar Rats Using Data Analysis" @default.
• W3025704615 cites W1708140731 @default.
• W3025704615 cites W1921213883 @default.
• W3025704615 cites W1961515348 @default.
• W3025704615 cites W1963610284 @default.
• W3025704615 cites W1968132547 @default.
• W3025704615 cites W1993543839 @default.
• W3025704615 cites W2026613788 @default.
• W3025704615 cites W2031414482 @default.
• W3025704615 cites W2041041704 @default.
• W3025704615 cites W2042462625 @default.
• W3025704615 cites W2045782183 @default.
• W3025704615 cites W2049163404 @default.
• W3025704615 cites W2052917647 @default.
• W3025704615 cites W2056606217 @default.
• W3025704615 cites W2073640336 @default.
• W3025704615 cites W2074735069 @default.
• W3025704615 cites W2078028705 @default.
• W3025704615 cites W2078805519 @default.
• W3025704615 cites W2083399904 @default.
• W3025704615 cites W2104294082 @default.
• W3025704615 cites W2124121471 @default.
• W3025704615 cites W2127110761 @default.
• W3025704615 cites W2138608577 @default.
• W3025704615 cites W2144976913 @default.
• W3025704615 cites W2166354753 @default.
• W3025704615 cites W2345328813 @default.
• W3025704615 cites W2351893496 @default.
• W3025704615 cites W2469833812 @default.
• W3025704615 cites W2520222164 @default.
• W3025704615 cites W2586966203 @default.
• W3025704615 cites W2677466604 @default.
• W3025704615 cites W2791957820 @default.
• W3025704615 cites W2906752223 @default.
• W3025704615 cites W324135019 @default.
• W3025704615 cites W4212949515 @default.
• W3025704615 doi "https://doi.org/10.3390/molecules25102353" @default.
• W3025704615 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7287681" @default.
• W3025704615 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32443550" @default.
• W3025704615 hasPublicationYear "2020" @default.
• W3025704615 type Work @default.
• W3025704615 sameAs 3025704615 @default.
• W3025704615 citedByCount "12" @default.
• W3025704615 countsByYear W30257046152020 @default.
• W3025704615 countsByYear W30257046152021 @default.
• W3025704615 countsByYear W30257046152022 @default.
• W3025704615 countsByYear W30257046152023 @default.
• W3025704615 crossrefType "journal-article" @default.
• W3025704615 hasAuthorship W3025704615A5023151211 @default.
• W3025704615 hasAuthorship W3025704615A5034929369 @default.
• W3025704615 hasAuthorship W3025704615A5042569868 @default.
• W3025704615 hasAuthorship W3025704615A5043001329 @default.
• W3025704615 hasAuthorship W3025704615A5045705864 @default.
• W3025704615 hasAuthorship W3025704615A5047927390 @default.
• W3025704615 hasAuthorship W3025704615A5058920839 @default.
• W3025704615 hasAuthorship W3025704615A5065873883 @default.
• W3025704615 hasAuthorship W3025704615A5083806306 @default.
• W3025704615 hasBestOaLocation W30257046151 @default.
• W3025704615 hasConcept C105083479 @default.
• W3025704615 hasConcept C126322002 @default.
• W3025704615 hasConcept C134018914 @default.
• W3025704615 hasConcept C135870905 @default.
• W3025704615 hasConcept C2776165026 @default.
• W3025704615 hasConcept C2777431362 @default.
• W3025704615 hasConcept C2777477808 @default.
• W3025704615 hasConcept C2778945730 @default.
• W3025704615 hasConcept C42407357 @default.
• W3025704615 hasConcept C515207424 @default.
• W3025704615 hasConcept C55493867 @default.
• W3025704615 hasConcept C62231903 @default.
• W3025704615 hasConcept C71924100 @default.
• W3025704615 hasConcept C86803240 @default.
• W3025704615 hasConcept C99476002 @default.
• W3025704615 hasConceptScore W3025704615C105083479 @default.
• W3025704615 hasConceptScore W3025704615C126322002 @default.
• W3025704615 hasConceptScore W3025704615C134018914 @default.
• W3025704615 hasConceptScore W3025704615C135870905 @default.
• W3025704615 hasConceptScore W3025704615C2776165026 @default.
• W3025704615 hasConceptScore W3025704615C2777431362 @default.
• W3025704615 hasConceptScore W3025704615C2777477808 @default.
• W3025704615 hasConceptScore W3025704615C2778945730 @default.
• W3025704615 hasConceptScore W3025704615C42407357 @default.
• W3025704615 hasConceptScore W3025704615C515207424 @default.
• W3025704615 hasConceptScore W3025704615C55493867 @default.
• W3025704615 hasConceptScore W3025704615C62231903 @default.

• next