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• W3025834433 abstract "A new synthesis of LYS228, fitting for further process development for commercial manufacture, is described. The key features of this synthesis include development of new protocols for acylation reactions, application of an asymmetric hydrogenation via dynamic kinetic resolution, and a late-stage ring closure to form β-lactam 1." @default.
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• W3025834433 date "2020-05-15" @default.
• W3025834433 modified "2023-10-16" @default.
• W3025834433 title "New Synthesis for the Monobactam Antibiotic—<b>LYS228</b>" @default.
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• W3025834433 doi "https://doi.org/10.1021/acs.joc.9b01916" @default.
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