FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3025908517> ?p ?o ?g. }

• W3025908517 endingPage "47" @default.
• W3025908517 startingPage "41" @default.
• W3025908517 abstract "Objectives To investigate the potential protective influence of serum uric acid (UA) level on white matter (WM) microstructural changes in de novo Parkinson's disease (PD). Methods We enrolled a total of 184 patients with drug-naïve de novo PD and 59 age and gender-matched controls that underwent diffusion tensor imaging (DTI). Based on the distribution, serum UA levels were stratified into tertiles in PD patients by gender. Using tract-based spatial statistics (TBSS) analysis, fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) were used to compare WM integrity between the groups. Results Interaction analysis showed that interaction effect on FA values between gender and UA levels in PD was significant in widespread WM areas, including frontal-parieto-temporal, corpus callosum, bilateral internal and external capsule, and thalamic regions. Multiple regression analysis revealed that FA values had a significantly positive correlation with UA levels across widespread WM areas in male patients. However, there was no significant correlation between DTI measures and UA levels in female patients. In a group comparison in male patients, PD with the lowest UA level (PD-L-UA) group showed significantly lower FA and higher MD and RD values in frontal-parieto-temporal WM regions than PD with the highest UA level (PD-H-UA) group. However, female patients did not show significant difference of DTI measures between PD-L-UA and PD-H-UA groups. Conclusions The present study demonstrated that the serum UA levels may have the potentially gender-specific close relationship with WM integrity in the early stage of PD." @default.
• W3025908517 created "2020-05-21" @default.
• W3025908517 creator A5040024146 @default.
• W3025908517 creator A5042630648 @default.
• W3025908517 creator A5051185462 @default.
• W3025908517 creator A5063288871 @default.
• W3025908517 creator A5066886061 @default.
• W3025908517 creator A5087676439 @default.
• W3025908517 creator A5091665783 @default.
• W3025908517 date "2020-06-01" @default.
• W3025908517 modified "2023-10-13" @default.
• W3025908517 title "Gender-specific effect of urate on white matter integrity in Parkinson's disease" @default.
• W3025908517 cites W1819667273 @default.
• W3025908517 cites W1832537945 @default.
• W3025908517 cites W1999372065 @default.
• W3025908517 cites W2004006028 @default.
• W3025908517 cites W2006115845 @default.
• W3025908517 cites W2010634472 @default.
• W3025908517 cites W2014380567 @default.
• W3025908517 cites W2015778757 @default.
• W3025908517 cites W2016250122 @default.
• W3025908517 cites W2022687465 @default.
• W3025908517 cites W2025372788 @default.
• W3025908517 cites W2059476756 @default.
• W3025908517 cites W2073449985 @default.
• W3025908517 cites W2091024837 @default.
• W3025908517 cites W2103295393 @default.
• W3025908517 cites W2106179404 @default.
• W3025908517 cites W2109572793 @default.
• W3025908517 cites W2121816670 @default.
• W3025908517 cites W2141463585 @default.
• W3025908517 cites W2154878289 @default.
• W3025908517 cites W2163584809 @default.
• W3025908517 cites W2166609052 @default.
• W3025908517 cites W2290281188 @default.
• W3025908517 cites W2592910636 @default.
• W3025908517 cites W2737227438 @default.
• W3025908517 cites W2793868633 @default.
• W3025908517 cites W2804892965 @default.
• W3025908517 cites W2861203326 @default.
• W3025908517 cites W2900977366 @default.
• W3025908517 doi "https://doi.org/10.1016/j.parkreldis.2020.05.012" @default.
• W3025908517 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32474403" @default.
• W3025908517 hasPublicationYear "2020" @default.
• W3025908517 type Work @default.
• W3025908517 sameAs 3025908517 @default.
• W3025908517 citedByCount "7" @default.
• W3025908517 countsByYear W30259085172020 @default.
• W3025908517 countsByYear W30259085172021 @default.
• W3025908517 countsByYear W30259085172023 @default.
• W3025908517 crossrefType "journal-article" @default.
• W3025908517 hasAuthorship W3025908517A5040024146 @default.
• W3025908517 hasAuthorship W3025908517A5042630648 @default.
• W3025908517 hasAuthorship W3025908517A5051185462 @default.
• W3025908517 hasAuthorship W3025908517A5063288871 @default.
• W3025908517 hasAuthorship W3025908517A5066886061 @default.
• W3025908517 hasAuthorship W3025908517A5087676439 @default.
• W3025908517 hasAuthorship W3025908517A5091665783 @default.
• W3025908517 hasConcept C126322002 @default.
• W3025908517 hasConcept C126838900 @default.
• W3025908517 hasConcept C134018914 @default.
• W3025908517 hasConcept C142724271 @default.
• W3025908517 hasConcept C143409427 @default.
• W3025908517 hasConcept C149550507 @default.
• W3025908517 hasConcept C15744967 @default.
• W3025908517 hasConcept C164705383 @default.
• W3025908517 hasConcept C2777796809 @default.
• W3025908517 hasConcept C2778183499 @default.
• W3025908517 hasConcept C2779134260 @default.
• W3025908517 hasConcept C2779734285 @default.
• W3025908517 hasConcept C2779881121 @default.
• W3025908517 hasConcept C2781192897 @default.
• W3025908517 hasConcept C71924100 @default.
• W3025908517 hasConcept C89916169 @default.
• W3025908517 hasConcept C90924648 @default.
• W3025908517 hasConceptScore W3025908517C126322002 @default.
• W3025908517 hasConceptScore W3025908517C126838900 @default.
• W3025908517 hasConceptScore W3025908517C134018914 @default.
• W3025908517 hasConceptScore W3025908517C142724271 @default.
• W3025908517 hasConceptScore W3025908517C143409427 @default.
• W3025908517 hasConceptScore W3025908517C149550507 @default.
• W3025908517 hasConceptScore W3025908517C15744967 @default.
• W3025908517 hasConceptScore W3025908517C164705383 @default.
• W3025908517 hasConceptScore W3025908517C2777796809 @default.
• W3025908517 hasConceptScore W3025908517C2778183499 @default.
• W3025908517 hasConceptScore W3025908517C2779134260 @default.
• W3025908517 hasConceptScore W3025908517C2779734285 @default.
• W3025908517 hasConceptScore W3025908517C2779881121 @default.
• W3025908517 hasConceptScore W3025908517C2781192897 @default.
• W3025908517 hasConceptScore W3025908517C71924100 @default.
• W3025908517 hasConceptScore W3025908517C89916169 @default.
• W3025908517 hasConceptScore W3025908517C90924648 @default.
• W3025908517 hasFunder F4320322120 @default.
• W3025908517 hasLocation W30259085171 @default.
• W3025908517 hasOpenAccess W3025908517 @default.
• W3025908517 hasPrimaryLocation W30259085171 @default.
• W3025908517 hasRelatedWork W1977877868 @default.
• W3025908517 hasRelatedWork W2017539237 @default.

• next