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- W3025996899 abstract "To characterize growth plate histology of porcine spines instrumented with a new intra-vertebral staple.Spinal segments (T7-T9) previously instrumented with an intra-vertebral staple (experimental group, n=7) or non-instrumented (control group, n=4) underwent average growth rate (AGR), and histomorphometric measurements: heights of proliferative (PZH) and hypertrophic (HZH) growth plate zones, hypertrophic cells height (CH), and the number of proliferative chondrocytes per column (CC). These measurements were done over three regions: (1) left side; (2) middle; (3) right side (instrumented side). The two groups were analyzed by comparing the difference between results for regions 1 and 3 (Dif-R1R3).A significantly higher Dif-R1R3 was found for AGR and HZH for the experimental group as compared with controls. This Dif-R1R3 was also significantly higher for CC at T8 level, CH at T7 level and PZH at both levels. No significant changes for the Dif-R1R3 were observed in the adjacent vertebrae (T11-T12).This study confirmed the local growth modulation capacity of the intra-vertebral staple, translated at the histomorphometric level by a significant reduction in all parameters, but not in all spinal levels. Further analyses are needed to confirm the regional effect, especially for the intervertebral disc and other connective tissues." @default.
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- W3025996899 date "2019-03-01" @default.
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- W3025996899 title "Mechanobiological analysis of porcine spines instrumented with intra-vertebral staples." @default.
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