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- W3026089025 abstract "Background Acute-on-chronic liver failure due to hepatitis B virus infection is a subtype of liver failure. The aim of the current study was to investigate the clinical significance of serum lactic acid in combination with the Chronic Liver Failure-Sequential Organ Failure Assessment score (CLIF-SOFA) for evaluating the short-term prognosis of HBV-related ACLF patients.Research design and methods The serum lactic acid level, the score model for end-stage liver disease (MELD), as well as the CLIF-SOFA of inpatients with HBV-related ACLF who were admitted to the Liver Disease Center of the First Affiliated Hospital of Fujian Medical University between 2009 and 2017 were analyzed.Results Three hundred and ninety-one HBV-related ACLF inpatients were measured. In the survival group, the lactate clearance rate measured over the course of 1 week post-admission was significantly higher than that measured for the death group. The area under the curve (AUC) for predicting the prognosis of HBV-related ACLF patients in short-term (within 3-month) with a baseline lactic acid level was 0.776.Conclusions Prediction performance of the short-term prognosis of HBV-related ACLF patients by combining the lactic acid level into the CLIF-SOFA score was significantly improved in comparison to using the CLIF-SOFA score alone." @default.
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- W3026089025 date "2020-05-20" @default.
- W3026089025 modified "2023-10-03" @default.
- W3026089025 title "Combining the serum lactic acid level and the lactate clearance rate into the CLIF-SOFA score for evaluating the short-term prognosis of HBV-related ACLF patients" @default.
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- W3026089025 doi "https://doi.org/10.1080/17474124.2020.1763172" @default.
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