FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3026284313> ?p ?o ?g. }

• W3026284313 endingPage "115446" @default.
• W3026284313 startingPage "115446" @default.
• W3026284313 abstract "Cortical bone thinning and a rarefaction of the trabecular architecture represent possible causes of increased femoral neck (FN) fracture risk. Due to X-ray exposure limits, the bone microstructure is rarely measurable in the FN of subjects but can be assessed at the tibia. Here, we studied whether changes of the tibial cortical microstructure, which were previously reported to be associated with femur strength, are also associated with structural deteriorations of the femoral neck. The cortical and trabecular architectures in the FN of 19 humans were analyzed ex vivo on 3D microcomputed tomography images with 30.3 μm voxel size. Cortical thickness (Ct.Thtibia), porosity (Ct.Potibia) and pore size distribution in the tibiae of the same subjects were measured using scanning acoustic microscopy (12 μm pixel size). Femur strength during sideways falls was simulated with homogenized voxel finite element models. Femur strength was associated with the total (vBMDtot; R2 = 0.23, p < 0.01) and trabecular (vBMDtrab; R2 = 0.26, p < 0.01) volumetric bone mineral density (vBMD), with the cortical thickness (Ct.ThFN; R2 = 0.29, p < 0.001) and with the trabecular bone volume fraction (Tb.BV/TVFN; R2 = 0.34, p < 0.001), separation (Tb.SpFN; R2 = 0.25, p < 0.01) and number (Tb.NFN; R2 = 0.32, p < 0.001) of the femoral neck. Moreover, smaller Ct.Thtibia was associated with smaller Ct.ThFN (R2 = 0.31, p < 0.05), lower Tb.BV/TVFN (R2 = 0.29, p < 0.05), higher Tb.SpFN (R2 = 0.33, p < 0.05) and lower Tb.NFN (R2 = 0.42, p < 0.01). A higher prevalence of pores with diameter > 100 μm in tibial cortical bone (relCt.Po100μm-tibia) indicated higher Tb.SpFN (R2 = 0.36, p < 0.01) and lower Tb.NFN (R2 = 0.45, p < 0.01). Bone resorption and structural decline of the femoral neck may be identified in vivo by measuring cortical bone thickness and large pores in the tibia." @default.
• W3026284313 created "2020-05-29" @default.
• W3026284313 creator A5020926615 @default.
• W3026284313 creator A5024351344 @default.
• W3026284313 creator A5032185441 @default.
• W3026284313 creator A5040691815 @default.
• W3026284313 creator A5044304481 @default.
• W3026284313 creator A5045900735 @default.
• W3026284313 creator A5047298821 @default.
• W3026284313 creator A5057271492 @default.
• W3026284313 creator A5060236332 @default.
• W3026284313 creator A5080019211 @default.
• W3026284313 date "2020-08-01" @default.
• W3026284313 modified "2023-09-30" @default.
• W3026284313 title "Cortical thinning and accumulation of large cortical pores in the tibia reflect local structural deterioration of the femoral neck" @default.
• W3026284313 cites W1527935003 @default.
• W3026284313 cites W1547714734 @default.
• W3026284313 cites W1803711505 @default.
• W3026284313 cites W1964983194 @default.
• W3026284313 cites W1969293769 @default.
• W3026284313 cites W1971580199 @default.
• W3026284313 cites W1972173398 @default.
• W3026284313 cites W1977670839 @default.
• W3026284313 cites W1977921830 @default.
• W3026284313 cites W1983023120 @default.
• W3026284313 cites W1988471370 @default.
• W3026284313 cites W2001369830 @default.
• W3026284313 cites W2012074412 @default.
• W3026284313 cites W2014973716 @default.
• W3026284313 cites W2015313580 @default.
• W3026284313 cites W2015487918 @default.
• W3026284313 cites W2023425023 @default.
• W3026284313 cites W2044628039 @default.
• W3026284313 cites W2047242396 @default.
• W3026284313 cites W2047490936 @default.
• W3026284313 cites W2049646783 @default.
• W3026284313 cites W2056810908 @default.
• W3026284313 cites W2057868965 @default.
• W3026284313 cites W2065509691 @default.
• W3026284313 cites W2065651226 @default.
• W3026284313 cites W2074150342 @default.
• W3026284313 cites W2077765377 @default.
• W3026284313 cites W2080179323 @default.
• W3026284313 cites W2081735229 @default.
• W3026284313 cites W2100465806 @default.
• W3026284313 cites W2104935228 @default.
• W3026284313 cites W2112488161 @default.
• W3026284313 cites W2120490103 @default.
• W3026284313 cites W2139590151 @default.
• W3026284313 cites W2140375955 @default.
• W3026284313 cites W2143581825 @default.
• W3026284313 cites W2144424358 @default.
• W3026284313 cites W2147917524 @default.
• W3026284313 cites W2151064671 @default.
• W3026284313 cites W2274511626 @default.
• W3026284313 cites W2288931164 @default.
• W3026284313 cites W2586325787 @default.
• W3026284313 cites W2611628065 @default.
• W3026284313 cites W2770783826 @default.
• W3026284313 cites W2792588985 @default.
• W3026284313 cites W2799846891 @default.
• W3026284313 cites W2803471940 @default.
• W3026284313 cites W2803887274 @default.
• W3026284313 cites W2805147219 @default.
• W3026284313 cites W2808989419 @default.
• W3026284313 cites W2884791777 @default.
• W3026284313 cites W2912273811 @default.
• W3026284313 cites W2967845986 @default.
• W3026284313 cites W2981469195 @default.
• W3026284313 cites W3016089321 @default.
• W3026284313 doi "https://doi.org/10.1016/j.bone.2020.115446" @default.
• W3026284313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32450342" @default.
• W3026284313 hasPublicationYear "2020" @default.
• W3026284313 type Work @default.
• W3026284313 sameAs 3026284313 @default.
• W3026284313 citedByCount "9" @default.
• W3026284313 countsByYear W30262843132020 @default.
• W3026284313 countsByYear W30262843132021 @default.
• W3026284313 countsByYear W30262843132022 @default.
• W3026284313 crossrefType "journal-article" @default.
• W3026284313 hasAuthorship W3026284313A5020926615 @default.
• W3026284313 hasAuthorship W3026284313A5024351344 @default.
• W3026284313 hasAuthorship W3026284313A5032185441 @default.
• W3026284313 hasAuthorship W3026284313A5040691815 @default.
• W3026284313 hasAuthorship W3026284313A5044304481 @default.
• W3026284313 hasAuthorship W3026284313A5045900735 @default.
• W3026284313 hasAuthorship W3026284313A5047298821 @default.
• W3026284313 hasAuthorship W3026284313A5057271492 @default.
• W3026284313 hasAuthorship W3026284313A5060236332 @default.
• W3026284313 hasAuthorship W3026284313A5080019211 @default.
• W3026284313 hasBestOaLocation W30262843132 @default.
• W3026284313 hasConcept C105702510 @default.
• W3026284313 hasConcept C126838900 @default.
• W3026284313 hasConcept C141071460 @default.
• W3026284313 hasConcept C142724271 @default.
• W3026284313 hasConcept C192562407 @default.
• W3026284313 hasConcept C2775854910 @default.
• W3026284313 hasConcept C2776541429 @default.

• next