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• W3026741320 abstract "A hierarchical mixed-effects model is proposed to account for both individual- and population-level variability in human immunodeficiency virus (HIV) dynamics. This model is implemented by formulating the crucial parameters as random variables in an in-host HIV model. Model reduction is used to guide the choice for a minimal set of parameters, whose distributions are estimated by the global two-stage method. We analyze the system of ordinary differential equations with random coefficients and provide numerical simulations illustrating its asymptotic behaviors." @default.
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• W3026741320 date "2020-01-01" @default.
• W3026741320 modified "2023-10-16" @default.
• W3026741320 title "Hierarchical Mixed-Effects Model for HIV Dynamics" @default.
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• W3026741320 doi "https://doi.org/10.1137/19m1246031" @default.
• W3026741320 hasPublicationYear "2020" @default.
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