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- W30267602 abstract "Avian leukemia viruses comprise a class of retroviruses isolated in their majority from field cases of the domestic chicken. A group of these agents, which are defective for replication and are therefore referred to as “defective leukemia viruses” (DLV), cause a variety of types of acute leukemia and other neoplasms of nonhematopoietic origin within weeks or months after infection. All DLV-strains isolated so far are capable of in vitro transformation of hematopoietic tissues (for review see Graf and Beug, 1978). In our recent studies, we have mainly concentrated on two model virus strains: avian erythroblastosis virus (AEV) and myelocytomatosis virus strain MC29. Clone-purified AEV causes an acute erythroleukemia but also sarcomas (Graf et al., 1977). MC29 causes myelocytomatosis and tumors of predominantly epitheloid origin (for references, see Graf and Beug, 1978)." @default.
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- W30267602 date "1979-01-01" @default.
- W30267602 modified "2023-09-27" @default.
- W30267602 title "Mechanism of Leukemogenesis and of Target Cell Specificity by Defective Avian Leukemia Viruses: A Hypothesis" @default.
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- W30267602 doi "https://doi.org/10.1007/978-3-642-67057-2_57" @default.
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